Results 1 to 10 of about 50 (50)
The arabidopsis cyclic nucleotide interactome [PDF]
Cell Communication and Signaling, 2016 Cyclic nucleotides have been shown to play important signaling roles in many physiological processes in plants including photosynthesis and defence. Despite this, little is known about cyclic nucleotide-dependent signaling mechanisms in plants since the downstream target proteins remain unknown.
Lara Donaldson +3 more
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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel
Nature Structural & Molecular Biology, 2023 Cyclic nucleotide-gated ion channels are crucial in many physiological processes such as vision and pacemaking in the heart. SthK is a prokaryotic homolog with high sequence and structure similarities to hyperpolarization-activated and cyclic nucleotide-modulated and cyclic nucleotide-gated channels, especially at the level of the cyclic nucleotide ...
Yangang Pan +6 more
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Compartmentation of Cyclic Nucleotide Signaling in the Heart [PDF]
Circulation Research, 2006 A current challenge in cellular signaling is to decipher the complex intracellular spatiotemporal organization that any given cell type has developed to discriminate among different external stimuli acting via a common signaling pathway. This obviously applies to cAMP and cGMP signaling in the heart, where these cyclic nucleotides determine the ...
Fischmeister, Rodolphe +6 more
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Sources of Cyclic Nucleotides in Plasma [PDF]
Journal of Clinical Investigation, 1974 In order to determine the sites of net production and removal of the cyclic nucleotides in plasma, various blood vessels were catheterized in 17 anesthetized dogs and arterial and venous concentrations of adenosine 3',5'-monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) were measured by radioimmunoassay. Aortic cAMP was 30+/-2 nM (mean+/-SE)
Robert E. Wehmann +2 more
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Cyclic nucleotides and amphibian development
Experimental Cell Research, 1975 Summary Addition of 3′, 5′-cyclic AMP (cAMP), N 6 , O 2 dibutyryl cyclic AMP (db-cAMP) and 3′,5′-cyclic GMP (cGMP) to fertilized amphibian eggs ( Ambystoma mexicanum, Xenopus laevis ) exerted little effect on development. Theophylline, at a high concentration (10 mM), produced strong developmental abnormalities; it had no effect at lower ...
Pays Deschutter, Annette +3 more
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Some of the next articles are maybe not open access.
Phytochemistry, 2004
The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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Saturation of anti cyclic nucleotides antibodies by endogenous cyclic nucleotides
Biochemical and Biophysical Research Communications, 1979Abstract Rabbits immunized against cyclic AMP or cyclic GMP produce antibodies which are fully saturated by their respective endogenous cyclic nucleotides. This was proved a) in comparing radioimmunological measurements of cyclic nucleotides in antiserum and the binding site concentration determined by equilibrium dialysis, b) in showing the ...
Michel Delaage, H.L. Cailla, D. Roux
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Chemistry of Cyclic Nucleotides and Cyclic Nucleotide Analogs
1982Since the isolation and characterization of cAMP in early 1957, several enzymatic and chemical synthetic procedures have been developed to provide cAMP and various cyclic nucleotide analogs. The synthesis of cAMP and 2′-deoxy-cAMP by bacterial fermentation is of current commercial interest as a low cost source of nucleoside 3′,5′-cyclic phosphates.
G. R. Revankar, R. K. Robins
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Cyclic Nucleotide Immunohistochemistry
Journal of Histotechnology, 1981AbstractIt has been reported that cyclic nucleotide immunohistochemistry fails to localize all pools of cyclic nucleotides and to detect the changes in cyclic nucleotide concentration when applied to unfixed brain tissue sections. Losses of cyclic nucleotides during antibody incubations have been demonstrated, but it has not been determined whether ...
Thomas P. Hartz, Ladislav Volicer
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