Results 21 to 30 of about 50 (50)
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Cyclic Nucleotide Metabolism in Tumours
Australian and New Zealand Journal of Medicine, 1979Summary: Many hormones act by combining with cell surface receptors and stimulating adenylate cyclase activity. The cyclic AMP generated is the mediator of a number of cellular metabolic processes. Other processes may be influenced by changes in cyclic GMP levels.
T. J. Martin, N. H. Hunt
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1982
The events taking place intracellularly within the central nervous system when pyrogens, putative neurotransmitters or other pharmacologically active substances raise body temperature during fever are poorly understood. Recognition of cyclic AMP as an intracellular mediator of adrenaline and glucagon-induced activation of hepatic glycolysis (Sutherland
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The events taking place intracellularly within the central nervous system when pyrogens, putative neurotransmitters or other pharmacologically active substances raise body temperature during fever are poorly understood. Recognition of cyclic AMP as an intracellular mediator of adrenaline and glucagon-induced activation of hepatic glycolysis (Sutherland
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Cyclic Nucleotide Phosphodiesterases
2000In multicellular organisms, cell functions are integrated through a large network of signals and homeostatic mechanisms that control the intracellular concentration of second messengers. This is a feature indispensable for the basal functions of the body, as well as for an efficient response to the continuous changes in the environment to which the ...
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Prostaglandins and Cyclic Nucleotides
1982The literature on the interactions of prostaglandins (PGs) and cyclic nucleotides is growing at an ever increasing rate; despite this fact, it is still very difficult to integrate the different and often conflicting reports into a unified picture.
R. Paoletti, S. Nicosia
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Cyclic nucleotides in nervous tissue
Brain Research Bulletin, 1978A review of the literature emphasizes that cyclic nucleotides play a key role in regulation of cell growth, differentiation and metabolism in diverse tissues and, in addition, are closely involved in neural tissue function. The role of cAMP as a second messenger is discussed.
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Cyclic Nucleotide Metabolism [PDF]
, 1983 This chapter deals with the enzymes that synthesize and degrade cyclic nucleotides in the central nervous system. The actions of the cyclic nucleotides themselves were reviewed in Volume 1 of this series.
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1988
Publisher Summary This chapter describes methods for the extraction and measurement of cyclic nucleotides, their typical intracellular concentrations, and the estimation of the activities of adenylate cyclase and cAMP phosphodiesterase. Some details of the tetra- and pentaphosphates of guanosine (ppGpp and pppGpp), although not cyclic nucleotides ...
Khalil Elmorjani, Michael Herdman
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Publisher Summary This chapter describes methods for the extraction and measurement of cyclic nucleotides, their typical intracellular concentrations, and the estimation of the activities of adenylate cyclase and cAMP phosphodiesterase. Some details of the tetra- and pentaphosphates of guanosine (ppGpp and pppGpp), although not cyclic nucleotides ...
Khalil Elmorjani, Michael Herdman
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EXTRACELLULAR CYCLIC NUCLEOTIDES*
Annals of the New York Academy of Sciences, 1971Earl W. Sutherland +5 more
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Accumulation of Cyclic Nucleotides
1977The complexity of the interrelationships of the cyclases, phosphodiesterases, protein kinases, and phosphoprotein phosphatases with macromolecular factors, magnesium, manganese, and calcium ions, and levels of ATP and GTP and, in addition, the existence of multiple enzyme forms with differing properties even within one cell make it difficult or ...
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