Results 31 to 40 of about 592,204 (244)
Tester investigates fundamental factors affecting cyclic life and sealing performance of valve seats and poppets. Tester provides for varying impact loading of poppet against seat and rate of cycling, and controls amount and type of relative motion ...
Tellier, G. F.
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Deterministic Constructions of Binary Measurement Matrices from Finite Geometry [PDF]
Deterministic constructions of measurement matrices in compressed sensing (CS) are considered in this paper. The constructions are inspired by the recent discovery of Dimakis, Smarandache and Vontobel which says that parity-check matrices of good low ...
Jiang, Yong +3 more
core
A Second Order Non-Smooth Variational Model for Restoring Manifold-Valued Images
We introduce a new non-smooth variational model for the restoration of manifold-valued data which includes second order differences in the regularization term.
Bačák, Miroslav +3 more
core +1 more source
Cyclic performance of steel and composite bracing members [PDF]
Abstract This paper describes an experimental study on the response of hollow and filled steel members to monotonic and cyclic axial loading. Monotonic tests were first performed on short specimens to establish their compressive and tensile axial resistances and to investigate the effect of infill on local buckling and ductility.
B.M. Broderick +2 more
openaire +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On Zone-Based Analysis of Duration Probabilistic Automata
We propose an extension of the zone-based algorithmics for analyzing timed automata to handle systems where timing uncertainty is considered as probabilistic rather than set-theoretic.
Ahmed Rezine +4 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source

