Results 11 to 20 of about 523,816 (270)
Total Synthesis of Pagoamide A
Molecules, 2021 The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous ...
Fusong Wu +4 more
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Synthesis and stereochemistry of 6-membered ring phosphonates [PDF]
QScience Connect, 2012 Background: Organophosphorus compounds have important industrial and biomedical applications as pharmaceutical and agrochemical agents, as well as transition state analogs for the production of monoclonal antibodies.
Michael D. Pungente, Larry Weiler
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Oncogene-induced DNA damage: cyclic AMP steps into the ring [PDF]
Journal of Clinical Investigation, 2020 Growth hormone-secreting (GH-secreting) pituitary tumors are driven by oncogenes that induce cAMP signaling. In this issue of the JCI, Ben-Shlomo et al. performed a whole-exome study of pituitary adenomas. GH-secreting tumors had a high frequency of whole chromosome or chromosome arm copy number alterations and were associated with an increase in the ...
James A, Fagin, John H, Petrini
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Super-Acceleration with Cyclical Step-sizes
, 2021 We develop a convergence-rate analysis of momentum with cyclical step-sizes. We show that under some assumption on the spectral gap of Hessians in machine learning, cyclical step-sizes are provably faster than constant step-sizes. More precisely, we develop a convergence rate analysis for quadratic objectives that provides optimal parameters and shows ...
Goujaud, Baptiste +4 more
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Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
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Water on Mars: Do submarine cyclic steps exist on the red planet?
Progress in Earth and Planetary Science, 2018 Submarine cyclic steps have a significant impact on the evolution of the ocean floor on Earth. These upper-flow regime bedforms should be even more common in Martian reduced-gravity environments.
Svetlana Kostic, Isaac B. Smith
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Structurally Cyclic Petri Nets [PDF]
Logical Methods in Computer Science, 2015 A Petri net is structurally cyclic if every configuration is reachable from itself in one or more steps. We show that structural cyclicity is decidable in deterministic polynomial time.
Drewes Frank, Leroux Jérôme
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Green Energy & Environment, 2023 Synthesizing ring structure aviation fuels from biomass-derived platform molecules is challenging, especially for bridged ring structure aviation fuels which are typically achieved from fossil-derived chemicals.
Zhanchao Li +4 more
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Cyclic networks of quantum gates [PDF]
, 2002 In this article initial steps in an analysis of cyclic networks of quantum logic gates is given. Cyclic networks are those in which the qubit lines are loops.
A. Barenco +14 more
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Kinesin's backsteps under mechanical load [PDF]
, 2009 Kinesins move processively toward the plus end of microtubules by hydrolyzing ATP for each step. From an enzymatic perspective, the mechanism of mechanical motion coupled to the nucleotide chemistry is often well explained using a single-loop cyclic ...
Alberty +71 more
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