Results 121 to 130 of about 904,141 (304)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Exchange Rate Volatility and the extent of Currency Substitution in Nigeria [PDF]

This study tests for the existence of currency substitution and attempts to gauge its magnitude in Nigeria. The analysis was based on a multi-perspective unrestricted portfolio balance model.
Yinusa, D. Olalekan, Akinlo, A.E.
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ELECTROCHEMICAL BEHAVIOR OF CaBaCo₂O₅±δ IN NEUTRAL AQUEOUS SOLUTION

Studia Universitatis Babes-Bolyai Chemia, 2015
This paper presents the effect of Y3+ substitution with Ca2+ ions on the electrochemical behavior of Y-112 perovskite in neutral aqueous solution during oxygen insertion/release.
Mircea Laurențiu DAN, Nicolae VASZILCSIN, Narcis Mihai DUŢEANU   +2 more
doaj  

One‐Step Aqueous Synthesis of Glycosyl Pyridinium Salts, Electrochemical Study, and Assessment of Utility as Precursors of Glycosyl Radicals Using Photoredox Catalysis

ChemistryOpen
A single step method for the production of unprotected glycosyl pyridinium salts has been developed involving treatment of the unprotected sugar with a pyridine, triethylamine, and either 2‐chloro‐1,3‐dimethylimidazolinium chloride (DMC) or 2‐chloro‐1,3 ...
Daniel Chong, Paula A. Brooksby, Antony J. Fairbanks   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Cyclic response of RC beam-column joints reinforced with plain bars: an experimental testing campaign [PDF]

, 2012
Existing reinforced concrete (RC) buildings constructed until the mid-70’s, with plain reinforcing bars, are expected to behave poorly when subjected to earthquake actions.
Costa, A., Melo, J., Varum, H., Rossetto, T.   +3 more
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

ELASTICITY OF SUBSTITUTION BETWEEN LABOUR AND CAPITAL ACROSS TWENTY SIX MAJOR INDUSTRIES IN INDIA DURING 2004-05 [PDF]

The magnitude of the elasticity of substitution between labour and capital across twenty six major Industries [Factory Sector] in India has been estimated in the present paper by fitting a Constant Elasticity of Substitution Production Function for the ...
UPENDER, M.
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Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Elasticities of Substitution and Complementarity [PDF]

This paper is a modern synthesis of the more than seventy years of literature on the elasticity of substitution. At times, authors, such as Mundlak, have provided syntheses of the literature but these often seem to be forgotten by later authors and ...
David I. Stern
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