Results 41 to 50 of about 6,206 (257)
The Cyclicality of Immigrant Wages and Labour Market Flows: Evidence from Spain
Economics: Journal Articles, 2022 This article studies the responses of real wages and labour market flows of immigrants in Spain for the period between 1999 and 2019. By using Labour Force Survey microdata, I examine the cyclicality of job-finding and job-separation rates for immigrants
Gálvez-Iniesta Ismael
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
RECEPTION AND EXTRAPOLATION AS MEANS OF FORMATION AND TRANSFORMATION OF STATE LEGAL SYSTEMS
Правовое государство: теория и практикаThe problem of this article is a scientific discussion on determining the place and role of law reception and extrapolation in the process of formation and transformation of state legal systems, with an emphasis on the comparative historical ...
ROMASHOV Roman Anatolevich
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Financial Crises Between the 20th and 21st Centuries [PDF]
Ovidius University Annals: Economic Sciences Series, 2018 The economic crisis that hit the world economy in the summer of 2007 is unprecedented in postwareconomic history. Although the current crisis has many features in common with past similarrecession episodes.
Oprișan Oana, Țileagă Cosmin
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
The Cyclicality of Bank Credit Losses and Capital Ratios under Expected Loss Model
, 2023 We model the evolution of stylised bank loan portfolios to assess the impact of IFRS 9 and US GAAP expected loss model (ECL) on the cyclicality of loan loss provisions (LLPs), realised losses and capital ratios of banks, relative to the incurred loss ...
Steven Ongena +2 more
core +1 more source
The Cyclicality of Loan Loss Provision in Brazilian Commercial Banks
BBR: Brazilian Business Review, 2018 Debates on banking regulation have increasingly given rise to a discussion on the relationship between the loan loss provision and business cycles. Provisioning rules for credit losses for banks in Brazil have mixed system characteristics, which could ...
Antônio Maria Henri Beyle de Araújo +2 more
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source