Results 221 to 230 of about 382,305 (392)

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function. [PDF]

Sci Adv, 2023
Piol D, Tosatto L, Zuccaro E, Anderson EN, Falconieri A, Polanco MJ, Marchioretti C, Lia F, White J, Bregolin E, Minervini G, Parodi S, Salvatella X, Arrigoni G, Ballabio A, La Spada AR, Tosatto SCE, Sambataro F, Medina DL, Pandey UB, Basso M, Pennuto M.   +21 more
europepmc   +1 more source

Synthesis, Molecular Docking, and Biological Studies of New Naphthalene‐1,4‐Dione‐Linked Phenylpiperazine and Thioether

Chemistry &Biodiversity, EarlyView.
Synthesis, Molecular Docking, and Biological Studies of New Naphthalene‐1,4‐dione Linked Phenylpiperazine and Thioether. ABSTRACT Quinones are an important family of chemical compounds that are used in the development of anticancer drugs. Due to the anticancer properties of quinones, this study aims to investigate the antiproliferative and ...
Berrin Yilmaz, Nahide Gulsah Deniz, Cigdem Sayil, Ozlem Bingol Ozakpinar, Merve Gurboga, Turgut Sekerler, Pervin Rayaman, Erkan Rayaman, Elif Caliskan Salihi   +8 more
wiley   +1 more source

Mechanistic Roles of Transcriptional Cyclin-Dependent Kinases in Oncogenesis: Implications for Cancer Therapy. [PDF]

Cancers (Basel)
Alrouji M, Alshammari MS, Anwar S, Venkatesan K, Shamsi A.   +4 more
europepmc   +1 more source

Long-lasting complete remission in a patient with systemic metastases of recurrent breast cancer treated with cyclin-dependent kinases 4/6 inhibitors: a case report. [PDF]

J Med Case Rep, 2023
Yoneto T, Hasumi K, Takahashi N, Seki N, Takeda Y, Yoshimoto T.   +5 more
europepmc   +1 more source

Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK)

, 1998
Mahitosh Mandal, Debdutta Bandyopadhyay, Thea M. Goepfert, Rakesh Kumar   +3 more
openalex   +1 more source

Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. [PDF]

, 1995
Sergei Kuchin, Paula Yeghiayan, Marian Carlson   +2 more
openalex   +1 more source

In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins

ChemBioChem, Accepted Article.
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska, Jan Hendrik Illies, T. Moritz Weber   +2 more
wiley   +1 more source

Efficacy of cyclin-dependent kinases 4 and 6 inhibitors in the treatment of HR +/HER2 - advanced breast cancer: a meta-analysis. [PDF]

Eur J Med Res
Danbala IA, Wang X, Su Y, Tang H, Sheng W, Shaibu Z, Isah I, Yuan X.   +7 more
europepmc   +1 more source

Macromolecular High‐Affinity Binding Probed by Advanced Fluorescence Techniques

ChemBioChem, EarlyView.
For interacting biomolecules in solution, confocal fluorescence microscopy enables some very effective approaches to characterize intermolecular binding in complex sample environments and with small sample consumption. These approaches range from fluorescence‐based genetically encoded biosensors for use in living cells to the high controllability in ...
Alida Meyer, Benno Schedler, Jörg Fitter   +2 more
wiley   +1 more source