Results 1 to 10 of about 233,773 (266)
Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction [PDF]
EMBO Journal, 2000 The key regulator of G(2)-M transition of the cell cycle is M-phase promoting factor (MPF), a complex composed of cdc2 and a B-type cyclin. Cyclin B1 nuclear localization involves phosphorylation within a region called the cytoplasmic retention signal, which also contains a nuclear export signal.
Daniel Donoghue
exaly +5 more sources
Discovery of molecular and genetic mechanisms of cell cycle regulation: 2001 Nobel laureates leland Hartwell, Timothy Hunt and Paul Nurse [PDF]
The Ukrainian Biochemical Journal, 2023 Leland Hartwell, Paul Nurse and Timothy Hunt in 2001 were awarded the Nobel Prize for their discovery of molecular and genetic mechanisms of the cell cycle.
O. P. Matyshevska +3 more
doaj +1 more source
Novel CRK-Cyclin Complex Controls Spindle Assembly Checkpoint in Toxoplasma Endodyogeny
mBio, 2022 Opportunistic parasites of the Apicomplexa phylum use a variety of division modes built on two types of cell cycles that incorporate two distinctive mechanisms of mitosis: uncoupled from and coupled to parasite budding.
Lauren M. Hawkins +5 more
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Frontiers in Microbiology, 2022 The larval stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), one of the most lethal helminthic infections in humans.
Chonglv Feng +13 more
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FEBS Open Bio, 2022 Overexpression of human epidermal growth factor receptor 2 (HER2) in various cancers is correlated with poor patient survival. Trastuzumab, a recombinant humanized monoclonal antibody against HER2, has been considered to be a first‐line therapy for HER2 ...
Ratih Kusumastuti +6 more
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Frontiers in Genetics, 2022 The purpose of this study was clarify the relationship between the differential expression of cyclins CCNB1 and CCNG1 and chondrocyte damage in Kashin-Beck disease. Systematic review and high-throughput sequencing of chondrocytes derived from Kashin-Beck
Kaidiriye Setiwalidi +20 more
doaj +1 more source
Structural insights into the functional diversity of the CDK–cyclin family [PDF]
Open Biology, 2018 Since their characterization as conserved modules that regulate progression through the eukaryotic cell cycle, cyclin-dependent protein kinases (CDKs) in higher eukaryotic cells are now also emerging as significant regulators of transcription, metabolism
Daniel J. Wood, Jane A. Endicott
doaj +1 more source
Frontiers in Microbiology, 2021 Codon usage bias (the preferential use of certain synonymous codons (optimal) over others is found at the organism level (intergenomic) within specific genomes (intragenomic) and even in certain genes.
Loreto Arias +7 more
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Frontiers in Plant Science, 2022 The D-type cyclin (CYCD) gene, as the rate-limiting enzyme in the G1 phase of cell cycle, plays a vital role in the process of plant growth and development. Early studies on plant cyclin mostly focused on herbs, such as Arabidopsis thaliana.
Zhongnan Zhao +6 more
doaj +1 more source
The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells
Mycobiology, 2020 Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent prostate cancer cell line ...
Cheng-Yen Chiang +6 more
doaj +1 more source