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Translational control of cyclins [PDF]

Cell Division, 2011
Regulation of cyclin levels is important for many cell cycle-related processes and can occur at several different steps of gene expression. Translational regulation of cyclins, which occurs by a variety of regulatory mechanisms, permits a prompt response
Lai Ming-Chih, Tarn Woan-Yuh
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Immunomodulatory Roles of Cell Cycle Regulators

Frontiers in Cell and Developmental Biology, 2019
Core cell cycle regulators, including cyclin-dependent kinases (CDKs), cyclins, and cyclin-dependent kinase inhibitors (CKIs), are known for their well-characterized roles in cell division.
Phatthamon Laphanuwat, Siwanon Jirawatnotai   +1 more
doaj   +1 more source

Comprehensive and quantitative analysis of G1 cyclins. A tool for studying the cell cycle.

PLoS ONE, 2019
In eukaryotes, the cell cycle is driven by the actions of several cyclin dependent kinases (CDKs) and an array of regulatory proteins called cyclins, due to the cyclical expression patterns of the latter. In yeast, the accepted pattern of cyclin waves is
Elisabet Bállega, Reyes Carballar, Bàrbara Samper, Natalia Ricco, Mariana P Ribeiro, Samuel Bru, Javier Jiménez, Josep Clotet   +7 more
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Phylogenetic analysis of cell-cycle regulatory proteins within the Symbiodiniaceae

Scientific Reports, 2020
In oligotrophic waters, cnidarian hosts rely on symbiosis with their photosynthetic dinoflagellate partners (family Symbiodiniaceae) to obtain the nutrients they need to grow, reproduce and survive.
Lucy M. Gorman, Shaun P. Wilkinson, Sheila A. Kitchen, Clinton A. Oakley, Arthur R. Grossman, Virginia M. Weis, Simon K. Davy   +6 more
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Cyclins and CDKs in the regulation of meiosis-specific events

Frontiers in Cell and Developmental Biology, 2022
How eukaryotic cells control their duplication is a fascinating example of how a biological system self-organizes specific activities to temporally order cellular events.
Inés Palacios-Blanco, Cristina Martín-Castellanos   +1 more
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Cardiac insulin-like growth factor-1 and cyclins gene expression in canine models of ischemic or overpacing cardiomyopathy

BMC Cardiovascular Disorders, 2009
Background Insulin-like growth factor-1 (IGF-1), transforming growth factor β (TGFβ) and cyclins are thought to play a role in myocardial hypertrophic response to insults.
Da Costa Agnes, Hadad Ielham, Touihri Karim, Mathieu Myrielle, Mahmoudabady Maryam, Naeije Robert, Mc Entee Kathleen   +6 more
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The Impact of Proinflammatory M1 Macrophages on the Proliferation and Expression of Cyclin E2, Mitogen-Activated Protein Kinases 4 and 7 in Hepatocytes Isolated from a Diethylnitrosamine-Induced Hepatocellular Carcinoma Rat Model

Molecules
Background: Hepatocellular carcinoma (HCC) is highly resistant to conventional therapies, highlighting the need for novel immunotherapeutic approaches. In the tumor microenvironment (TME), the role of proinflammatory M1 macrophages remains ambiguous. The
Marta Wójcik, Luisa Pozzo, Andrea Vornoli, Vincenzo Longo, Anna Śmiech, Joanna Czerwik-Marcinkowska, Iwona Rozempolska-Rucińska, Agnieszka Chrapko, Szymon Zmorzynski   +8 more
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Drug-Free Approach To Study the Unusual Cell Cycle of Giardia intestinalis

mSphere, 2017
Giardia intestinalis is a protozoan parasite that causes giardiasis, a form of severe and infectious diarrhea. Despite the importance of the cell cycle in the control of proliferation and differentiation during a giardia infection, it has been difficult ...
Kathleen Horlock-Roberts, Chase Reaume, Guillem Dayer, Christine Ouellet, Nicholas Cook, Janet Yee   +5 more
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The regulation of cyclin D promoters – review

Cancer Treatment and Research Communications, 2021
Cyclins are key regulators of cell cycle progression and survival. Particularly cyclins D (cyclin D1, D2, and D3) act in response to the mitogenic stimulation and are pivotal mediators between proliferative pathways and the nuclear cell cycle machinery ...
Jan Pawlonka, Beata Rak, Urszula Ambroziak   +2 more
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The Prognostic Value and Overexpression of Cyclin A Is Correlated with Gene Amplification of both Cyclin A and Cyclin E in Breast Cancer Patient

Cellular Oncology, 2006
Deregulation of cell cycle control is a hallmark of cancer. The primary cyclins (A, B1, D1, D3 and E) are crucial for cell cycle progression. Secondary cyclins (C and H) have putative indirect effects on cell cycle propulsion and are not previously ...
A. Husdal, G. Bukholm, I. R. K. Bukholm
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