Results 11 to 20 of about 32,826 (263)

AaCycTL Regulates Cuticle and Trichome Development in Arabidopsis and Artemisia annua L.

Frontiers in Plant Science, 2021
Artemisinin is an important drug for resistance against malaria. Artemisinin is derived from the glandular trichome of leaves, stems, or buds of the Chinese traditional herb Artemisia annua.
Boran Dong, Boran Dong, Xingxing Wang, Xingxing Wang, Rui Jiang, Rui Jiang, Shiyuan Fang, Shiyuan Fang, Jinxing Li, Jinxing Li, Qing Li, Zong you Lv, Zong you Lv, Wan sheng Chen, Wan sheng Chen, Wan sheng Chen   +15 more
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Integrative analysis of physiology, biochemistry and transcriptome reveals the mechanism of leaf size formation in Chinese cabbage (Brassica rapa L. ssp. pekinensis)

Frontiers in Plant Science, 2023
IntroductionThe leaf, the main product organ, is an essential factor in determining the Chinese cabbage growth, yield and quality.MethodsTo explore the regulatory mechanism of leaf size development of Chinese cabbage, we investigated the leaf size ...
Lixia Wang, Shu Zhang, Ye Zhang, Jingjuan Li, Yihui Zhang, Dandan Zhou, Dandan Zhou, Cheng Li, Lilong He, Huayin Li, Fengde Wang, Jianwei Gao   +11 more
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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma

Cells, 2022
Pancreatic cancer is a leading cause of cancer mortality and is projected to become the second-most common cause of cancer mortality in the next decade. While gene-wide association studies and next generation sequencing analyses have identified molecular
Cristina Di Giorgio, Antonio Lupia, Silvia Marchianò, Martina Bordoni, Rachele Bellini, Carmen Massa, Ginevra Urbani, Rosalinda Roselli, Federica Moraca, Valentina Sepe, Bruno Catalanotti, Elva Morretta, Maria Chiara Monti, Michele Biagioli, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +16 more
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Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery

Frontiers in Oncology, 2020
Increased protein synthesis is a key process in melanoma, which is regulated by the ALDH18A1 gene encoding pyrroline-5-carboxylate synthase (P5CS). P5CS is involved in proline biosynthesis and targeting ALDH18A1 has previously been shown to inhibit ...
Gregory R. Kardos, Gregory R. Kardos, Gregory R. Kardos, Raghavendra Gowda, Raghavendra Gowda, Raghavendra Gowda, Saketh Sriram Dinavahi, Saketh Sriram Dinavahi, Saketh Sriram Dinavahi, Scot Kimball, Gavin P. Robertson, Gavin P. Robertson, Gavin P. Robertson, Gavin P. Robertson, Gavin P. Robertson, Gavin P. Robertson   +15 more
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Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors

BMC Research Notes, 2009
Background The cell cycle is promoted by activation of cyclin dependent kinases (Cdks), which are regulated positively by cyclins and negatively by Cdk inhibitors. Proliferation of carcinoma is associated with altered regulation of the cell cycle. Little
Collan Yrjö, Vahlberg Tero, Palokangas Tuire, Söderström Mirva, Boström Pia, Carpen Olli, Hirsimäki Pirkko   +6 more
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Identification of Arabidopsis meiotic cyclins reveals functional diversification among plant cyclin genes.

PLoS Genetics, 2013
Meiosis is a modified cell division in which a single S-phase is followed by two rounds of chromosome segregation resulting in the production of haploid gametes.
Petra Bulankova, Svetlana Akimcheva, Nicole Fellner, Karel Riha   +3 more
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Expression of cyclins A and E in melanocytic skin lesions and its correlation with some clinicopathologic features

Folia Histochemica et Cytobiologica, 2012
Cyclins play a fundamental role in the cell cycle. Recent studies have focused on their role in the development of various malignancies. The objective of this study was to evaluate and compare the expression of cyclins A and E in common nevi, dysplastic ...
Ana Alekseenko, Anna Wojas-Pelc, Grzegorz J. Lis, Zdzisław Wiśniowski, Magdalena Czerwińska, Łukasz Niewiara, Jan A. Litwin   +6 more
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LIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression. [PDF]

PLoS ONE, 2014
Cell cycle transitions are governed by the timely expression of cyclins, the activating subunits of Cyclin-dependent kinases (Cdks), which are responsible for the inactivation of the pocket proteins.
Frank Eckerdt, Mathew Perez-Neut, Oscar R Colamonici   +2 more
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Molecular evolution of cyclin proteins in animals and fungi

BMC Evolutionary Biology, 2011
Background The passage through the cell cycle is controlled by complexes of cyclins, the regulatory units, with cyclin-dependent kinases, the catalytic units.
Afonnikov Dmitry A, Turnaev Igor I, Suslov Valentin V, Gunbin Konstantin V, Kolchanov Nikolay A   +4 more
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Divide or Commit – Revisiting the Role of Cell Cycle Regulators in Adult Hippocampal Neurogenesis

Frontiers in Cell and Developmental Biology, 2019
The adult dentate gyrus continuously generates new neurons that endow the brain with increased plasticity, helping to cope with changing environmental and cognitive demands.
Anja Urbach, Otto W. Witte
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