Results 21 to 30 of about 37,065 (297)
Biology, 2023 Timely mitosis is critically important for early embryo development. It is regulated by the activity of the conserved protein kinase CDK1. The dynamics of CDK1 activation must be precisely controlled to assure physiologic and timely entry into mitosis ...
Mohammed El Dika +3 more
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Two-way communication between cell cycle and metabolism in budding yeast: what do we know?
Frontiers in Microbiology, 2023 Coordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes.
Yanfei Zhang +5 more
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Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction [PDF]
The EMBO Journal, 2000 The key regulator of G(2)-M transition of the cell cycle is M-phase promoting factor (MPF), a complex composed of cdc2 and a B-type cyclin. Cyclin B1 nuclear localization involves phosphorylation within a region called the cytoplasmic retention signal, which also contains a nuclear export signal.
Kong, Monica +3 more
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Emerging Mechanisms of G1/S Cell Cycle Control by Human and Mouse Cytomegaloviruses
mBio, 2021 Cytomegaloviruses (CMVs) are among the largest pathogenic viruses in mammals. To enable replication of their long double-stranded DNA genomes, CMVs induce profound changes in cell cycle regulation.
Boris Bogdanow +2 more
doaj +1 more source
Prediction of Cyclin Protein Using Two-Step Feature Selection Technique
IEEE Access, 2020 Cyclins are a family of proteins that regulate the cell cycle by activating cyclin-dependent kinases or a group of enzymes required in the cell cycle. Constructing a model to classify Cyclins is of importance to understand their function. It is urgent to
Jia-Nan Sun +6 more
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D-Type Cyclins in Development and Disease [PDF]
, 2023 D-type cyclins encode G1/S cell cycle checkpoint proteins, which play a crucial role in defining cell cycle exit and progression. Precise control of cell cycle exit is vital during embryonic development, with defects in the pathways regulating ...
Poulter, J.A. +5 more
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AaCycTL Regulates Cuticle and Trichome Development in Arabidopsis and Artemisia annua L.
Frontiers in Plant Science, 2021 Artemisinin is an important drug for resistance against malaria. Artemisinin is derived from the glandular trichome of leaves, stems, or buds of the Chinese traditional herb Artemisia annua.
Boran Dong +15 more
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Frontiers in Plant Science, 2023 IntroductionThe leaf, the main product organ, is an essential factor in determining the Chinese cabbage growth, yield and quality.MethodsTo explore the regulatory mechanism of leaf size development of Chinese cabbage, we investigated the leaf size ...
Lixia Wang +11 more
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Cells, 2022 Pancreatic cancer is a leading cause of cancer mortality and is projected to become the second-most common cause of cancer mortality in the next decade. While gene-wide association studies and next generation sequencing analyses have identified molecular
Cristina Di Giorgio +16 more
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The regulation of CDK activity by cyclins [PDF]
, 2021 In eukaryotes, the two major cell cycle events of DNA replication and chromosome segregation are directed by Cyclin Dependent Kinases (CDKs) in combination with G1/S cyclins (S-CDK) and G2/M cyclins (M-CDK), respectively.
Basu, Souradeep
core +1 more source