Results 21 to 30 of about 40,343 (298)
Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin–cyclin interaction [PDF]
The EMBO Journal, 2000 The key regulator of G(2)-M transition of the cell cycle is M-phase promoting factor (MPF), a complex composed of cdc2 and a B-type cyclin. Cyclin B1 nuclear localization involves phosphorylation within a region called the cytoplasmic retention signal, which also contains a nuclear export signal.
Kong, Monica +3 more
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Two-way communication between cell cycle and metabolism in budding yeast: what do we know?
Frontiers in Microbiology, 2023 Coordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes.
Yanfei Zhang +5 more
doaj +1 more source
Emerging Mechanisms of G1/S Cell Cycle Control by Human and Mouse Cytomegaloviruses
mBio, 2021 Cytomegaloviruses (CMVs) are among the largest pathogenic viruses in mammals. To enable replication of their long double-stranded DNA genomes, CMVs induce profound changes in cell cycle regulation.
Boris Bogdanow +2 more
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Prediction of Cyclin Protein Using Two-Step Feature Selection Technique
IEEE Access, 2020 Cyclins are a family of proteins that regulate the cell cycle by activating cyclin-dependent kinases or a group of enzymes required in the cell cycle. Constructing a model to classify Cyclins is of importance to understand their function. It is urgent to
Jia-Nan Sun +6 more
doaj +1 more source
Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]
, 2010 Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Sercombe, Heather E +3 more
core +4 more sources
AaCycTL Regulates Cuticle and Trichome Development in Arabidopsis and Artemisia annua L.
Frontiers in Plant Science, 2021 Artemisinin is an important drug for resistance against malaria. Artemisinin is derived from the glandular trichome of leaves, stems, or buds of the Chinese traditional herb Artemisia annua.
Boran Dong +15 more
doaj +1 more source
Frontiers in Plant Science, 2023 IntroductionThe leaf, the main product organ, is an essential factor in determining the Chinese cabbage growth, yield and quality.MethodsTo explore the regulatory mechanism of leaf size development of Chinese cabbage, we investigated the leaf size ...
Lixia Wang +11 more
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Living with or without cyclins and cyclin-dependent kinases [PDF]
Genes & Development, 2004 Entry into, progression through, and exit from the G1 phase of the mammalian cell cycle in response to extracellular mitogenic cues are presumed to be governed by cyclin-dependent kinases (Cdks) regulated by the D-type and E-type cyclins. Studies performed over more than a decade have supported the view that these holoenzymes are important, if not ...
Charles J, Sherr, James M, Roberts
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Cyclin E, a redundant cyclin in breast cancer [PDF]
Proceedings of the National Academy of Sciences, 1996 Cyclin E is an important regulator of cell cycle progression that together with cyclin-dependent kinase (cdk) 2 is crucial for the G 1 /S transition during the mammalian cell cycle. Previously, we showed that severe overexpression of cyclin E protein in tumor cells and tissues results in ...
J, Gray-Bablin +5 more
openaire +2 more sources
LIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression. [PDF]
PLoS ONE, 2014 Cell cycle transitions are governed by the timely expression of cyclins, the activating subunits of Cyclin-dependent kinases (Cdks), which are responsible for the inactivation of the pocket proteins.
Frank Eckerdt +2 more
doaj +1 more source