Results 21 to 30 of about 372,752 (258)

Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13

open access: yesFrontiers in Cell and Developmental Biology, 2019
Congenital heart defects, dysmorphic facial features and intellectual developmental disorders (CHDFIDD) syndrome in humans was recently associated with mutation in CDK13 gene.
Monika Nováková   +19 more
doaj   +1 more source

Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol [PDF]

open access: yes, 2008
Background Cyclin B1, the regulatory subunit of cyclin-dependent kinase 1 (Cdk1), is essential for the transition from G2 phase to mitosis. Cyclin B1 is very often found to be overexpressed in primary breast and cervical cancer cells as well as in cancer
Androic, Ilija   +23 more
core   +1 more source

Venezuelan Equine Encephalitis Virus Capsid Implicated in Infection-Induced Cell Cycle Delay in vitro

open access: yesFrontiers in Microbiology, 2018
Venezuelan equine encephalitis virus (VEEV) is a positive sense, single-stranded RNA virus and member of the New World alphaviruses. It causes a biphasic febrile illness that can be accompanied by central nervous system involvement and moderate morbidity
Lindsay Lundberg   +6 more
doaj   +1 more source

LGCI-Cyclin

open access: yes, 2023
This is the data and codes for identifying cyclin proteins.
Hongliang Zou (10916058)
core   +1 more source

Inhibitors of mammalian G1 cyclin-dependent kinases.

open access: yesGenes & Development, 1995
Biologic machines need brakes, and the nature and fidelity of their operation cannot be unraveled without some prior understanding of how accelerators work. The discoveD] of mammalian G1 cyclins just 4 years ago and the identification of their associated
C. Sherr, J. M. Roberts
semanticscholar   +1 more source

Cell Cycle Regulation in the Plant Response to Stress

open access: yesFrontiers in Plant Science, 2020
As sessile organisms, plants face a variety of environmental challenges. Their reproduction and survival depend on their ability to adapt to these stressors, which include water, heat stress, high salinity, and pathogen infection.
Feifei Qi, Fuxin Zhang
doaj   +1 more source

Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy

open access: yesOpen Biology, 2022
Measuring the dynamics with which the regulatory complexes assemble and disassemble is a crucial barrier to our understanding of how the cell cycle is controlled that until now has been difficult to address.
Martina Barbiero   +5 more
doaj   +1 more source

Cyclin E, a redundant cyclin in breast cancer [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
Cyclin E is an important regulator of cell cycle progression that together with cyclin-dependent kinase (cdk) 2 is crucial for the G 1 /S transition during the mammalian cell cycle. Previously, we showed that severe overexpression of cyclin E protein in tumor cells and tissues results in the appearance of lower ...
J, Gray-Bablin   +5 more
openaire   +2 more sources

CDK control pathways integrate cell size and ploidy information to control cell division

open access: yeseLife, 2021
Maintenance of cell size homeostasis is a property that is conserved throughout eukaryotes. Cell size homeostasis is brought about by the co-ordination of cell division with cell growth and requires restriction of smaller cells from undergoing mitosis ...
James Oliver Patterson   +3 more
doaj   +1 more source

Overexpression of Cyclin A and Cyclin B1Proteins in Astrocytomas

open access: yesArchives of Pathology & Laboratory Medicine, 2000
Abstract Background. —Cyclins are proteins that are expressed during the progression of a normal cell through the cell cycle. In a number of cancers, overexpression of cyclin A and cyclin B1 proteins has been reported, and in some instances the levels of expression correlated well with the ...
K, Allan   +4 more
openaire   +2 more sources

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