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Cyclin dependent kinase regulation

Current Opinion in Cell Biology, 1995
Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle and their activities are consequently tightly regulated. Recent developments in the field of CDK regulation have included the discovery and characterization of CDK inhibitors. These developments have had an impact on our understanding of how other signalling pathways may be linked to ...
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Cyclin-dependent kinases and stroke

Expert Opinion on Therapeutic Targets, 2001
Cyclin-dependent kinases (CDKs) are a group of enzymes predominately known for their role in cell cycle regulation in proliferating cell types. Increasing evidence, however, suggests that CDKs also promote death in neurones. These observations have lead to the notion that CDKs may serve as a therapeutic target for neuropathological conditions such as ...
Fuhu, Wang   +2 more
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Measuring Cyclin-Dependent Kinase Activity

2004
The activity of cyclin-dependent kinases (CDKs) lies at the heart of cell cycle and checkpoint control. These complexes have been called the "cell cycle engine," as it is their enzymatic activity that pushes the cells through the cell-division cycle.
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Cyclins, Cyclin-Dependent Kinases, and Cyclin-Dependent Kinase Inhibitors

2023
Nathan H. Lents   +1 more
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Cyclin-dependent protein kinases

2000
Abstract Cyclin-dependent protein kinases (Cdks) regulate progression through the eukaryotic cell cycle. They are also involved in the regulation of other processes such as gene expression and phosphate metabolism. Cdks are the catalytic subunits of hetero dimeric complexes and they approximate the size of a minimal protein-kinase ...
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Cyclin-Dependent Kinases

2013
A. Camins, J.G. Pizarro, J. Folch
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