Results 61 to 70 of about 2,643,362 (304)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Stability of Transversal Hamilton Cycles and Paths

open access: yesThe Electronic Journal of Combinatorics
Given graphs $G_1,\ldots,G_s$ all on a common vertex set and a graph $H$ with $e(H) = s$, a copy of $H$ is transversal or rainbow if it contains one edge from each $G_i$. We establish a stability result for transversal Hamilton cycles: the minimum degree required to guarantee a transversal Hamilton cycle can be lowered as long as the graph collection ...
Yangyang Cheng, Katherine Staden
openaire   +3 more sources

Stabilizer theorems for even cycle matroids

open access: yesJournal of Combinatorial Theory, Series B, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guenin, Bertrand   +2 more
openaire   +4 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Cycling on the Verge? Exploring the Place of Utility Cycling in Contemporary New Zealand Transport Policy [PDF]

open access: yes, 2014
Efforts to increase cycling as a mode of transport (utility cycling) occur at central, regional and local levels of government through a range of supportive strategies, research, and guidelines.
Smith, Megan
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]

open access: yes, 2002
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B.   +4 more
core   +1 more source

Stability of Graph Pairs Involving Cycles

open access: yesGraphs and Combinatorics
A graph pair $(Γ, Σ)$ is called stable if $\aut(Γ)\times\aut(Σ)$ is isomorphic to $\aut(Γ\timesΣ)$ and unstable otherwise, where $Γ\timesΣ$ is the direct product of $Γ$ and $Σ$. A graph is called $R$-thin if distinct vertices have different neighbourhoods.
Xiaomeng Wang, Shou-Jun Xu, Sanming Zhou
openaire   +2 more sources

Political Stabilization Cycles in High Inflation Economies [PDF]

open access: yesJournal of Development Economics, 1995
High inflation economies often do not exhibit smooth inflationary processes, but rather stop-go cycles. This paper relates these stop-go episodes of inflation to a political cycle. The government can try to repress inflation until after the elections in order to increase the chances of being reelected.
Ernesto H. Stein, Jorge M. Streb
openaire   +3 more sources

TiO2 Nanobelt@Co9S8 Composites as Promising Anode Materials for Lithium and Sodium Ion Batteries

open access: yesNanomaterials, 2017
TiO2 anodes have attracted great attention due to their good cycling stability for lithium ion batteries and sodium ion batteries (LIBs and SIBs). Unfortunately, the low specific capacity and poor conductivity limit their practical application. The mixed
Yanli Zhou   +3 more
doaj   +1 more source

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