Thermal Decomposition of Cross-linked Polybutadiene and its Copolymers [PDF]
, 1999 Polybutadiene and two copolymers containing butadiene and styrene have been cross-linked by thermal processes, by the use of initiators in solution, and by intimately mixing an initiator with the polymer and then heating this blend.
Jiang, David D. +3 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A Concise Total Synthesis of (--)-Maoecrystal Z [PDF]
, 2011 The first total synthesis of (--)-maoecrystal Z is described. The key steps of the synthesis include a diastereoselective Ti^(III)-mediated reductive epoxide coupling reaction and a diastereoselective Sm^(II)-mediated reductive cascade cyclization ...
Cha, Jacob Y. +2 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Investigations on the Formation of 4-Aminobicyclo[2.2.2]-octanones
Molecules, 2005 Benzylidene acetone reacts with thiocyanates derived from secondary amines in a one-pot reaction to give 4-aminobicyclo[2.2.2]octan-2-ones. The reaction mixture was investigated for the presence of possible intermediates using GC-MS.
Robert Weis +5 more
doaj +1 more source
Investigating the cyclization of enediyne analogs using density functional theory [PDF]
, 2012 Enediynes are organic molecules that readily undergo a thermal rearrangement, now commonly known as the Bergman cyclization, to a cyclic para diradical form.
Estep, Dylan
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Research Progress on the Reaction of Carbon Dioxide with Hydrazones and Their Derivatives
MoleculesCO2, an abundant and renewable C1 source, presents significant potential for applications in organic synthesis. Hydrazones, recognized for their distinctive properties, exhibit high versatility in synthetic chemistry, facilitating numerous chemical ...
Hong-Xia Sun +12 more
doaj +1 more source
Synthesis of Novel 3H-Quinazolin-4-ones Containing Pyrazolinone, Pyrazole and Pyrimidinone Moieties
Molecules, 2003 The diazonium salt of 3-(4-aminophenyl)-2-methyl-3H-quinazolin-4-one (2a) and its 6-bromo derivative 2b reacted with some active methylene compounds, namely ethyl acetoacetate (3), ethyl cyanoacetate (4) and acetylacetone (5), to afford the corresponding
Abdel-Basset M. Shokr +3 more
doaj +1 more source
Formation of bridged bicycloalkenes via ring closing metathesis [PDF]
, 1998 Ring closing metathesis may be used in the formation of small ring bicycloalkenes from monocyclic diene ...
Grubbs, Robert H., Morehead, Andrew, Jr.
core +1 more source