Results 131 to 140 of about 2,874,801 (150)

Genome-Based Discovery of an Unprecedented Cyclization Mode in Fungal Sesterterpenoid Biosynthesis.

Journal of the American Chemical Society, 2016
Sesterterpenoids are a group of terpenoid natural products that are primarily biosynthesized via cyclization of the C25 linear substrate geranylfarnesyl pyrophosphate (GFPP).
M. Okada, Yudai Matsuda, Takaaki Mitsuhashi, Shotaro Hoshino, Takahiro Mori, Kazuya Nakagawa, Zhiyang Quan, Bin Qin, Huiping Zhang, F. Hayashi, H. Kawaide, I. Abe   +11 more
semanticscholar   +1 more source

Metal-Free Electrophilic Phosphination/Cyclization of Alkynes.

Journal of the American Chemical Society, 2017
A metal-free electrophilic phosphination reaction has been developed. Electrophilic phosphorus species generated in situ from secondary phosphine oxides and Tf2O smoothly couple with alkynes possessing pendant nucleophiles to afford the corresponding ...
Yuto Unoh, K. Hirano, M. Miura
semanticscholar   +1 more source

Visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids to coumarin derivatives under metal-free conditions.

Chemical Communications, 2015
A visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids has been developed. The arylsulfonylation of alkynes was performed at room temperature under metal-free conditions to generate coumarin derivatives with wide ...
Wen-Chao Yang, Shuai Yang, Pinhua Li, Lei Wang   +3 more
semanticscholar   +1 more source

Photocatalytic Radical Trifluoromethylation/Cyclization Cascade: Synthesis of CF3-Containing Pyrazolines and Isoxazolines.

Organic Letters, 2015
A general visible light induced photoredox-catalyzed radical trifluoromethylation/cyclization cascade of β-aryl-β,γ-unsaturated hydrazones and oximes is described.
Q. Wei, Jia‐Rong Chen, Xiao-Qiang Hu, Xiao-chen Yang, Bin Lu, W. Xiao   +5 more
semanticscholar   +1 more source

Catalytic divergent synthesis of 3H or 1H pyrroles by [3 + 2] cyclization of allenoates with activated isocyanides.

Journal of the American Chemical Society, 2015
The cyclization of allenoates with activated isocyanides was reported for the first time. While Ag catalysis led to an unprecedented enantioselective synthesis of 3H pyrroles, a simple procedure using PPh3 produced a wide range of polysubstituted 1H ...
Jia-Yu Liao, Pan‐Lin Shao, Yu Zhao
semanticscholar   +1 more source

Enantioselective palladium-catalyzed dearomative cyclization for the efficient synthesis of terpenes and steroids.

Angewandte Chemie, 2015
A novel enantioselective palladium-catalyzed dearomative cyclization has been developed for the efficient construction of a series of chiral phenanthrenone derivatives bearing an all-carbon quaternary center.
K. Du, P. Guo, Yuan Chen, Zhengyan Cao, Zheng Wang, Wenjun Tang   +5 more
semanticscholar   +1 more source

Borylative Cyclization Reactions

, 2016
Borylative cyclizations constitute a family of important cascade reactions for the formation of carbo- and heterocycles containing boryl substituents.
E. Buñuel, Diego J. Cárdenas
semanticscholar   +1 more source

The organocatalytic asymmetric Prins cyclization.

Angewandte Chemie, 2015
We describe here the design and development of an organocatalytic Prins cyclization. In the presence of a confined chiral imidodiphosphoric acid catalyst, salicylaldehydes react with 3-methyl-3-buten-1-ol to afford highly functionalized 4 ...
G. Tsui, Luping Liu, B. List
semanticscholar   +1 more source

Robust, chiral, and porous BINAP-based metal-organic frameworks for highly enantioselective cyclization reactions.

Journal of the American Chemical Society, 2015
We report here the design of BINAP-based metal-organic frameworks and their postsynthetic metalation with Rh complexes to afford highly active and enantioselective single-site solid catalysts for the asymmetric cyclization reactions of 1,6-enynes. Robust,
T. Sawano, Nathan C. Thacker, Zekai Lin, A. McIsaac, Wenbin Lin   +4 more
semanticscholar   +1 more source

Palladium-catalyzed cyclization reactions of allenes in the presence of unsaturated carbon-carbon bonds.

Accounts of Chemical Research, 2014
Modern synthetic chemists have looked for rapid and efficient ways to construct complex molecules while minimizing synthetic manipulation and maximizing atom-economy.
Juntao Ye, Shengming Ma
semanticscholar   +1 more source