Results 31 to 40 of about 2,252 (131)

Integrative Toxicology Profiling of Thuja sutchuenensis Essential Oil: From LD50 Safety Assessment to Hepatic Apoptosis and Gut Microbiota Modulation

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This study provides the first experimental evidence of Thuja sutchuenensis essential oil (TEO) toxicity, with an oral LD50 of ~3800 mg/kg in mice. Sub‐LD50 doses cause focal hepatic necrosis via apoptosis/oxidative stress–related pathways without systemic inflammation or renal injury.
Nana Long, Youwei Zuo, Renxiu Yao, Quan Yang, Jian Li, Xiao Zhang, Shiqi You, Yang Peng, Hongping Deng   +8 more
wiley   +1 more source

Analysis of Plant Growth-Promoting Effects of Fluorescent Pseudomonas Strains Isolated from Mentha piperita Rhizosphere and Effects of Their Volatile Organic Compounds on Essential Oil Composition [PDF]

, 2016
Many species or strains of the genus Pseudomonas have been characterized as plant growth promoting rhizobacteria (PGPR). We used a combination of phenotypic and genotypic techniques to analyze the community of fluorescent Pseudomonas strains in the ...
Erika Banchio, Lorena del Rosario Cappellari, Maricel V. Santoro, Natalia Nocelli, Pablo C. Bogino, Walter F. Giordano   +5 more
core   +2 more sources

Pseudo‐Natural Products Inspired by Aspidospermidine‐, Strychnos‐, and Koumine Monoterpene Indole Alkaloids Reveal Pyrimidine Biosynthesis Inhibitors

Helvetica Chimica Acta, Volume 108, Issue 12, December 2025.
Chemical evolution of alkaloids inspired the synthesis of a monoterpene alkaloid‐inspired pseudo‐natural product compound collection and revealed a novel de novo pyrimidine biosynthesis inhibitor chemotype. ABSTRACT In pseudo‐natural product (PNP) design, natural product fragments are combined in arrangements not found in nature to afford novel ...
Animesh Biswas, Luca C. Greiner, Jana Bonowski, Axel Pahl, Sonja Sievers, Annika Schmidt, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann   +9 more
wiley   +1 more source

Synergistic O_3 + OH oxidation pathway to extremely low-volatility dimers revealed in β-pinene secondary organic aerosol [PDF]

, 2018
Dimeric compounds contribute significantly to the formation and growth of atmospheric secondary organic aerosol (SOA) derived from monoterpene oxidation. However, the mechanisms of dimer production, in particular the relevance of gas- vs.
Dalleska, Nathan F., Hethcox, J. Caleb, Huang, Yuanlong, Kenseth, Christopher M., Seinfeld, John H., Stoltz, Brian M., Zhao, Ran   +6 more
core   +1 more source

Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants [PDF]

, 2011
Background Indian medicinal plants used in the Ayurvedic traditional system to treat diabetes are a valuable source of novel anti-diabetic agents.
Sudha P, Smita S Zinjarde, Shobha Y Bhargava, Ameeta R Kumar   +3 more
core   +1 more source

Characterisation of Volatile Compounds Associated With the Flavour of Flatbreads: Effect of Sorghum, Cassava and Whole or Dehulled Red and White Cowpea Flours

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT This study characterised the volatile compounds in flatbreads prepared from red non‐tannin sorghum flour, cassava starch, whole and dehulled red and white cowpea flours and composite flours (30% cowpea flour and varying combinations of cassava starch and sorghum flour).
Rita Dankwa, Sefater Gbashi, Oluwafemi Ayodeji Adebo, Heikki Aisala, Eugenie Kayitesi, Henriette L. de Kock   +5 more
wiley   +1 more source

Photoredox‐Catalyzed Synthesis of a Novel Class of Fluoroalkyl Pyrazolones

Advanced Synthesis &Catalysis, Volume 367, Issue 21, November 13, 2025.
A photoredox strategy enables regioselective synthesis of fluoroalkyl 2‐pyrazolin‐5‐ones via radical addition and cyclization. This mild, metal‐free method shows a broad substrate scope, operates in batch and flow systems, and offers a sustainable approach to fluorinated heterocycles with potential applications in medicinal chemistry.
Emanuele F. Pissinati, Meysam Azizzade, Till Opatz, Márcio W. Paixão   +3 more
wiley   +1 more source

Estimates of Cl atom concentrations and hydrocarbon kinetic reactivity in surface air at Appledore Island, Maine (USA), during International Consortium for Atmospheric Research on Transport and Transformation/Chemistry of Halogens at the Isles of Shoals [PDF]

, 2007
Average hydroxyl radical (OH) to chlorine atom (Cl·) ratios ranging from 45 to 119 were determined from variability‐lifetime relationships for selected nonmethane hydrocarbons (NMHC) in surface air from six different transport sectors arriving at ...
Fischer, Emily V., Pszenny, Alexander A. P., Russo, Rachel S., Sive, Barkley C., Varner, Ruth K.   +4 more
core   +1 more source

Seasonal cycle and temperature dependence of pinene oxidation products, dicarboxylic acids and nitrophenols in fine and coarse air particulate matter [PDF]

, 2010
Filter samples of fine and coarse air particulate matter (PM) collected over a period of one year in central Europe (Mainz, Germany) were analyzed for water-soluble organic compounds (WSOCs), including the α- and β-pinene oxidation products pinic acid ...
G. K. Moortgat, L. Müller, R. Winterhalter, T. Hoffmann, U. Pöschl, Y. Y. Zhang   +5 more
core   +1 more source

Effects of Long‐Term Nutrient Addition on Leaf Metabolites, Herbivory, and Mycorrhizal Spores Associated With a Savannah Woody Species

Austral Ecology, Volume 50, Issue 11, November 2025.
ABSTRACT Given the importance of soil conditions for ecosystem functioning, fertilisation experiments are a valuable tool for assessing how systems respond to changes in soil properties. However, the effects of changes in nutrient availability on multitrophic interactions in savannah ecosystems of the Brazilian Cerrado are still scarce. We investigated
Alexandra Martins, Daniel Pecoraro Demarque, Renata Garcia Dusi, Camille Amorim Costa Santos, Laila Salmen Espindola, Mercedes Maria da Cunha Bustamante   +5 more
wiley   +1 more source