Results 1 to 10 of about 484 (123)

Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity

Molecules, 2022
The application of non-planar scaffolds in drug design allows for the enlargement of the chemical space, and for the construction of molecules that have more effective target–ligand interactions or are less prone to the development of resistance.
Kseniya N. Sedenkova, Kristian S. Andriasov, Marina G. Eremenko, Yuri K. Grishin, Vera A. Alferova, Anna A. Baranova, Nikolay A. Zefirov, Olga N. Zefirova, Vladimir V. Zarubaev, Yulia A. Gracheva, Elena R. Milaeva, Elena B. Averina   +11 more
doaj   +1 more source

Bis(oxiranes) Containing Cyclooctane Core: Synthesis and Reactivity towards NaN₃

Molecules, 2022
Reactions of oxirane ring opening provide a powerful tool for regio- and stereoselective synthesis of polyfunctional and heterocyclic compounds, widely used in organic chemistry and drug design.
Kseniya N. Sedenkova, Olga V. Ryzhikova, Svetlana A. Stepanova, Alexei D. Averin, Sergei V. Kositov, Yuri K. Grishin, Igor P. Gloriozov, Elena B. Averina   +7 more
doaj   +1 more source

Photonitrosation of Cyclooctane and Cyclododecane

The Journal of the Society of Chemical Industry, Japan, 1967
シクロアルカン類は光の存在下で塩化ニトロシルと反応して相当するシクロアルカノンオキシム塩酸塩を与えるが,このような光ニトロソ化反応におけるシクロヘキサン,シクロオクタン,シクロドデカンの反応挙動を比較検討した。シクロドデカンの場合は適当な溶媒の選択が重要であるが,シクロヘキサン(あるいはシクロオクタン)を溶媒として両者の混合反応を行なうことにより良好な結果を得た。また,これらの混合反応においてオキシム生成量の比を求めてシクロアルカンの反応性を比較した。(C8>C6≧C12)。
Yoichi SHIMOKAWA, Shigeru WAKAMATSU, Yoshikazu ITO   +2 more
openaire   +2 more sources

Highly substituted benzannulated cyclooctanol derivatives by samarium diiodide-induced cyclizations

Beilstein Journal of Organic Chemistry, 2010
A series of γ-oxo esters suitably substituted with various styrene subunits was subjected to samarium diiodide-induced 8-endo-trig cyclizations. Efficacy, regioselectivity and stereoselectivity of these reactions via samarium ketyls strongly depend on ...
Jakub Saadi, Irene Brüdgam, Hans-Ulrich Reissig   +2 more
doaj   +1 more source

Cyclooctane-1,2,5,6-tetrayl tetraacetate

Acta Crystallographica Section E Structure Reports Online, 2006
In the title compound, C16H24O8, the cyclo­octane ring has a non-planar structure. Weak inter­molecular C—H⋯O hydrogen bonding occurs in the crystal structure.
Yavuz, Metin, Salamci, Emine, Ustabas, Resat, Coruh, Ufuk, Vazquez-Lopez, Ezequiel M.   +4 more
openaire   +3 more sources

Straightforward Synthetic Approach to Aminoalcohols with 9-oxabicyclo[3.3.1]nonane or Cyclooctane Core via Nucleophilic Ring-Opening of Spirocyclic Bis(oxiranes)

Molecules
Nucleophilic ring-opening of bis(oxiranes), containing several reactive centers, can be used to elaborate straightforward atom-economy and stereoselective approaches to polyfunctionalized compounds.
Olga V. Ryzhikova, Daiana V. Savchenkova, Sergey V. Kositov, Yuri K. Grishin, Olga A. Maloshitskaya, Kseniya N. Sedenkova, Elena B. Averina   +6 more
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A whole cell biocatalyst for double oxidation of cyclooctane

Journal of Industrial Microbiology and Biotechnology, 2016
Abstract A novel whole cell cascade for double oxidation of cyclooctane to cyclooctanone was developed. The one-pot oxidation cascade requires only a minimum of reaction components: resting E. coli cells in aqueous buffered medium (=catalyst), the target substrate and oxygen as environmental friendly oxidant.
Müller, C. A., Weingartner, A. M., Dennig, A., Ruff, A. J., Gröger, Harald, Schwaneberg, Ulrich   +5 more
openaire   +3 more sources

Synthesis and Characterization of an Eight-Membered Heterocyclic 1,3,5,7-Tetra(3-pyridyl)-1,3,5,7-tetrazacyclooctane

SynOpen, 2023
Li Li, Guo-Liang Dai, Xue Hua Zhu, Lei Yu, Hai Yan Li   +4 more
doaj   +1 more source

Dominance number on cyclooctane chains

Vojnotehnicki glasnik
Introduction/purpose: Chemical structures are conveniently represented by graphs where atoms are nodes (vertices) and chemical bonds are branches (lines) in the graph. A graphical representation of a molecule provides a lot of useful information about the chemical properties of the molecule. It is known that numerous physical and chemical properties of
openaire   +2 more sources

Isomerization of Cyclooctane with Aluminium Chloride

The Journal of the Society of Chemical Industry, Japan, 1971
Iwao TABUSHI, Kahee FUJITA, Masaki TSUBOI, Ryohei ODA   +3 more
openaire   +2 more sources