Results 1 to 10 of about 505 (151)
Abstract The preparation and the addition reactions of 1,5-bismethylenecyclooctane are described, together with a novel synthesis of the bicyclo[3.3.2]decane ring system.
K.H. Baggaley +4 more
exaly +3 more sources
The cycloheptanes and cyclooctanes
Publisher Summary This chapter discusses cycloheptanes and cyclooctances, which are compounds containing more than seven or eight rings. Many of these compounds have been found to exhibit significant biochemical effects. The chemistry of monocyclic compounds with seven and eight membered rings is investigated in this chapter.
D.F. Ewing
exaly +3 more sources
Wacker Oxidation of Trisubstituted Alkenes: Pd(II)-Catalyzed Oxidative Ring Expansion of Exocyclic α,β-Unsaturated Carbonyl to 2-Fluoro-1,3-Dicarbonyl Compounds. [PDF]
First examples of Pd(II)‐catalyzed Wacker oxidation of trisubstituted alkenes, coupled with electrophilic fluorination, enable a one‐carbon ring expansion of exocyclic α,β‐unsaturated carbonyls to 2‐fluoro‐2‐acyl‐cycloalkanones. Abstract The Wacker oxidation is a powerful synthetic method widely employed for the transformation of monosubstituted ...
Goëlo V, Wang Q, Zhu J.
europepmc +3 more sources
ChemInform Abstract: The Cycloheptanes and Cyclooctanes
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
D. F. EWING
openaire +2 more sources
Straightforward Synthetic Approach to Aminoalcohols with 9-oxabicyclo[3.3.1]nonane or Cyclooctane Core via Nucleophilic Ring-Opening of Spirocyclic Bis(oxiranes) [PDF]
Nucleophilic ring-opening of bis(oxiranes), containing several reactive centers, can be used to elaborate straightforward atom-economy and stereoselective approaches to polyfunctionalized compounds.
Olga V. Ryzhikova +6 more
doaj +2 more sources
Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity
The application of non-planar scaffolds in drug design allows for the enlargement of the chemical space, and for the construction of molecules that have more effective target–ligand interactions or are less prone to the development of resistance.
Kseniya N. Sedenkova +11 more
doaj +1 more source
Bis(oxiranes) Containing Cyclooctane Core: Synthesis and Reactivity towards NaN3
Reactions of oxirane ring opening provide a powerful tool for regio- and stereoselective synthesis of polyfunctional and heterocyclic compounds, widely used in organic chemistry and drug design.
Kseniya N. Sedenkova +7 more
doaj +1 more source

