Results 231 to 240 of about 24,541,782 (296)

Effects on Oral Squamous Carcinoma Cell Lines and Their Mechanisms of Pyrazole N-Aryl Sulfonate: A Novel Class of Selective Cyclooxygenase-2 Inhibitors. [PDF]

Int J Mol Sci
Wang S, Shi M, Wang H, Zeng X, Zhang D, Zhang Z, Xu Z, Li Y.   +7 more
europepmc   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

Comparative effects of cyclooxygenase-2 selective and nonselective nonsteroidal anti-inflammatory drugs and acetaminophen on rotator cuff tendon-bone healing in a rat model. [PDF]

Acta Orthop Traumatol Turc
Bektaş E, Çelebi ME, Kurtulmuş T, Yılmaz F.   +3 more
europepmc   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

A sulfonimide derivative of bezafibrate as a dual inhibitor of cyclooxygenase-2 and PPARα. [PDF]

Front Pharmacol
Ammazzalorso A, Tacconelli S, Contursi A, Hofling U, Cerchia C, Di Berardino S, De Michele A, Amoroso R, Lavecchia A, Patrignani P.   +9 more
europepmc   +1 more source

The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children. [PDF]

BMC Pediatr
Zaki M, Orban HA, Shahba MA, Moustafa RSI, Adel A, Fadel FI, Selim A, El-Bassyouni HT, Youness ER.   +8 more
europepmc   +1 more source

Correction to "hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers". [PDF]

Mol Oncol
europepmc   +1 more source

Therapeutic efficacy of Rosa damascena Mill. on oxidative stress parameters and cyclooxygenase-2 gene expression in estradiol valerate-induced polycystic ovarian syndrome in Wistar rats. [PDF]

Sci Rep
Farhadi-Azar M, Mahboobifard F, Mousavi M, Naz MSG, Farahmand M, Yaghmaei P, Tehrani FR.   +6 more
europepmc   +1 more source

Pituitary adenylate cyclase-activating polypeptide mediates bacterial endotoxin-induced fever via an effect on cyclooxygenase-2 and inflammatory cytokines. [PDF]

Sci Rep
Sparks J, Furedi N, Fekete K, Solymar M, Pohoczky K, Kemeny A, Reglodi D, Garami A, Pakai E.   +8 more
europepmc   +1 more source

The Expression of Cyclooxygenase-2 in Cervical Intraepithelial Neoplasia and Cervical Cancer. [PDF]

Cureus
Shaik N, Nerune SM, Patil VS, Jawalkar S.   +3 more
europepmc   +1 more source