Results 1 to 10 of about 24,435,752 (203)

Protective Role of Cynara cardunculus L. var. altilis Against Oxidative Stress and Corneal Dysfunction in High Glucose-Damaged Human Corneal Epithelial Cells

Frontiers in Bioscience-Landmark
Background: The global increase in diabetes mellitus has been accompanied by a significant rise in related complications. Diabetic patients frequently experience ocular surface disorders and multiple studies have demonstrated that the ...
Carmelina Daniela Anfuso, Caterina Ledda, Alessia Cosentino, Aleksandra Agafonova, Chiara Prinzi, Sara Lombardo, Gaetano Pandino, Maria Scuto, Gabriella Lupo, Angela Trovato Salinaro   +9 more
doaj   +1 more source

Neuroprotective activity of Leontice leontopetalum extract against H2O2-stimulated oxidative stress in PC12 cells [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: Neuronal toxicity can be induced by oxidative stress via free radicals production. In recent years, great interest has been expressed to the traditional and herbal medicines.
S. Sahranavard*, S. Ghafari, M. Irani, B. Eslami Tehrani   +3 more
doaj  

Immunohistochemical expression of Cyclooxygenase-2 in colorectal carcinoma and its association with clinicopathological parameters

Zanco Journal of Medical Sciences, 2019
Background and objective: Inflammatory process and genetic factors play a key role in neoplasia of colorectal cancer. Cyclooxygenase-2 is involved in a variety of important cellular functions, including cell growth and differentiation, cancer cell ...
Payman MS. Salim, Saman S. Abdulla, Jalal A. Jalal   +2 more
doaj   +1 more source

Cyclo-Oxygenase 2 Modulates Chemoresistance in Breast Cancer Cells Involving NF-κB

Cellular Oncology, 2009
Background: Breast cancer cells can develop chemoresistance after prolonged exposure to cytotoxic drugs due to expression of the multi drug resistance (MDR) 1 gene.
Maria Chiara Zatelli, Daniela Molè, Federico Tagliati, Mariella Minoia, Maria Rosaria Ambrosio, Ettore Degli Uberti   +5 more
doaj   +1 more source

Cyclooxygenase 2-dependent and independent activation of Akt through casein kinase 2α contributes to human bladder cancer cell survival

BMC Urology, 2011
Background Survival rate for patients presenting muscle invasive bladder cancer is very low, and useful therapeutic target has not been identified yet. In the present study, new COX2 downstream signals involved in urothelial carcinoma cell survival were ...
Fujimoto Kiyohide, Marco Develasco A, Anai Satoshi, Shimada Keiji, Konishi Noboru   +4 more
doaj   +1 more source

Human Intelectin-1 (hITL-1) as Modulator of Metabolic Syndrome (MetS): An In Silico Study

Journal of Pharmacy and Bioallied Sciences
Human intelectin-1 (hITL-1) has been known to be involved in diseases such as asthma, cancer, metabolic disorders, and inflammatory bowel disease. In the present study, we aimed to evaluate hITL-1 as modulator of metabolic syndrome (MetS) using an in ...
Vishnupriya N, Narayanaswamy Radhakrishnan   +1 more
doaj   +1 more source

Endothelin-1 upregulates cyclooxygenase-2 expression and prostaglandin E2 synthesis in human periodontal ligament cells—an in vitro study

Journal of Orthodontic Science
AIMS: Endothelin-1 (ET-1) increased bone resorption during orthodontic tooth movement (OTM) in animal models, suggesting potential clinical applications for accelerating OTM.
Supachai Unmanatakoon, Supaporn Suttamanatwong   +1 more
doaj   +1 more source

Prostaglandin E2 promotes post‐infarction cardiomyocyte replenishment by endogenous stem cells

EMBO Molecular Medicine, 2014
Although self‐renewal ability of adult mammalian heart has been reported, few pharmacological treatments are known to promote cardiomyocyte regeneration after injury. In this study, we demonstrate that the critical period of stem/progenitor cell‐mediated
Ying‐Chang Hsueh, Jasmine M F Wu, Chun‐Keung Yu, Kenneth K Wu, Patrick C H Hsieh   +4 more
doaj   +1 more source

Corrigendum: Pyruvate kinase M2 promotes prostate cancer metastasis through regulating ERK1/2-COX-2 signaling

Frontiers in Oncology
Wenjing Guo, Wenjing Guo, Zhishuai Zhang, Guihuan Li, Xiaoju Lai, Ruonan Gu, Ruonan Gu, Wanfu Xu, Hua Chen, Zhe Xing, Liping Chen, Jiabi Qian, Shiyuan Xu, Fangyin Zeng, Fan Deng   +14 more
doaj   +1 more source

Relationship Between Selective Cyclooxygenase-2 Inhibitors and Acute Myocardial Infarction in Older Adults

Circulation, 2004
Daniel Solomon, Robert Glynn, Helen Mogun   +2 more
exaly