Results 31 to 40 of about 128,590 (304)

Cyclooxygenase-2 in Cardiovascular Biology

Clinical Medicine Insights: Cardiology, 2008
Cyclooxygenase (COX), also known as prostaglandin endoperoxide synthase, is the key enzyme required for the conversion of arachidonic acid to prostaglandins. Two COX isoforms have been identified, COX-1 and COX-2.
Joseph F. Murphy
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EICOSANOIDS AND INFLAMMATION

Современная ревматология, 2016
Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
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Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress

Emerging Microbes and Infections, 2022
The role of gut microbiota has been described as an important influencer of the immune system. Gut-lung axis is critical in the prevention of mycobacterium infection, but the specific mechanism, by which dysbiosis affects tuberculosis, has not been ...
Haoran Wang, Jiao Yao, Yulan Chen, Yuanzhi Wang, Yiduo Liu, Yi Liao, Zhengmin Liang, Yu hui Dong, Mengjin Qu, Xin Ge, Xiangmei Zhou   +10 more
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Cyclooxygenase 2 Promotes Proliferation and Invasion in Ovarian Cancer Cells via the PGE2/NF-κB Pathway

Cell Transplantation, 2019
Ovarian cancer is the leading cause of death among gynecological malignancies. Cyclooxygenase 2 is widely expressed in various cancer cells and participates in the occurrence and development of tumors by regulating a variety of downstream signaling ...
Xiao Zhang, Keqin Yan, Lin Deng, Jing Liang, Haiyan Liang, Dingqing Feng, Bin Ling   +6 more
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Cyclooxygenase-2 Expression in Bladder Cancer and Patient Prognosis: Results from a Large Clinical Cohort and Meta-Analysis [PDF]

, 2012
27/02/14 meb.
Manuel M. Morente (135761), Real, FX, Real, Francisco X., Morente, Manuel M., Kogevinas, Manolis, Adonina Tardón, SBC/EPICURO investigators, Real Francisco X., Montes-Moreno, S, Montes-Moreno Santiago, Carrato, Alfredo, Amaral André F. S., Maciej J Czachorowski, André F. S. Amaral (135752), Maciej J. Czachorowski (135750), Santiago Montes-Moreno, Czachorowski, Maciej J., Malats Núria, Morente, MM, Santiago Montes-Moreno (135753), Kogevinas, M, André F S Amaral, Manolis Kogevinas, Amaral, André F.S., Amaral, André F. S., Tardón Adonina, Czachorowski, Maciej J, Morente, Manuel M, Josep Lloreta, Manolis Kogevinas (135763), Francisco X Real, Carrato Alfredo, Alfredo Carrato (135757), Tardón, Adonina, Malats, N, Morente Manuel M., Montes Moreno, Santiago, Tardón García, Adonina, Czachorowski Maciej J., Núria Malats (135767), Malats i Riera, Núria, Kogevinas Manolis, Alfredo Carrato, Carrato, A, Francisco X. Real (135765), Adonina Tardón (135759), Montes-Moreno, Santiago, Lloreta, Josep, Josep Lloreta (135755), Malats Riera, Núria, Carrato Mena, Alfredo, Núria Malats, Lloreta Josep, Manuel M Morente, Tardón, A, Lloreta, J, Czachorowski, MJ, Amaral, AFS, Lloreta, Josep, 1958-   +58 more
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Epigallocatechin-3-gallate Blocks Triethylene Glycol Dimethacrylate-induced Cyclooxygenase-2 Expression by Suppressing Extracellular Signal-regulated Kinase in Human Dental Pulp and Embryonic Palatal Mesenchymal Cells [PDF]

, 2014
Introduction: Methacrylate resin-based materials could release components into adjacent environment even after polymerization. The major components leached include triethylene glycol dimethacrylate (TEGDMA). TEGDMA has been shown to induce the expression
章浩宏;張瑞青;郭彥彬;劉謙美, Yang, Wan-Hsien;Deng, Yi-Ting;Kuo, Mark Yen-Ping;Liu, Cheing-Meei;Chang, Hao-Hueng;Chang, Jenny Zwei-Chieng   +1 more
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Research progress on COX-2/PGE₂/EP₄ signaling axis in colon cancer

Zhongguo linchuang yanjiu, 2023
The expression of cyclooxygenase 2 (COX-2) was up-regulated and prostaglandin E2 (PGE2) was significantly increased in colon cancer patients. As the main prostaglandin produced by COX-2, PGE2 plays an important role in angiogenesis, survival, invasion ...
ZHENG Lirong, DU Haoyang, ZHANG Ruifen, ZHANG Hairong, BAO Aruhan, YU Lei, CUI Hongwei   +6 more
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Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia [PDF]

, 2014
© The Author 2014. Published by Oxford University Press This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution,
Pedersen, TL, Cortopassi, G, Newman, John W, Shen, Yan, Pedersen, Theresa L, Pook, Mark, Hayashi, G, Newman, JW, Pook, M, Hayashi, Genki, Cortopassi, Gino, Shen, Y   +11 more
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Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs) : a systematic structured review of the literature [PDF]

, 2007
Adverse events triggered by non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common drug-related intolerance reactions in medicine; they are possibly related to inhibition of cyclooxygenase-1.
Weberschock, Tobias Bernd Bernd, Boehncke, Wolf-Henning, Tobias Bernd Weberschock, Sylke-Monina Müller, Sandra Boehncke, Müller, Sylke-Monina, Wolf-Henning Boehncke, Weberschock, Tobias Bernd, Boehncke, Sandra   +8 more
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Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells

Journal of Lipid Research, 2004
Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induced ...
Martijn Schenning, Claudia M. van Tiel, Daniëlle van Manen, Jord C. Stam, Barend M. Gadella, Karel W.A. Wirtz, Gerry T. Snoek   +6 more
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