Results 261 to 270 of about 24,541,782 (296)
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Cyclooxygenase-2 and prostate carcinogenesis
Cancer Letters, 2003In recent years a dramatic surge has occurred on studies defining to the role of cyclooxygenase (COX)-2 in causation and prevention of cancer. Prostaglandin (PG) endoperoxidase synthase also commonly referred to as COX is a key enzyme involved in the conversion of arachidonic acid to PGs and other eicosanoids.
Tajamul, Hussain +2 more
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Cyclooxygenase-2 and kidney failure
Prostaglandins & Other Lipid Mediators, 2012Cyclooxygenase (COX)-dependent prostaglandins are necessary for normal kidney function. These prostaglandins are associated with inflammation, maintenance of sodium and water homeostasis, control of renin release, renal vasodilation, vasoconstriction attenuation, and prenatal renal development.
Amelia, Rios +3 more
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Cyclooxygenase-2 Expression in Chondrosarcoma
Oncology, 2004<i>Objective:</i> In recent years it has become evident that tissue cyclooxygenase-2 (COX-2) may play a role in carcinogenesis and tumor malignancy. There is now a mounting body of information that strongly implies that COX-2 inhibitors may be of some value in the management of patients with carcinomas, and most recently several similar ...
Karen M, Sutton +4 more
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Cyclooxygenase-2 selective inhibitors
Drugs of Today, 1999The identification of two cyclooxygenase (COX) enzymes has been a tremendous advance in understanding the role of prostaglandins in inflammation and the actions of nonsteroidal antiinflammatory drugs (NSAIDs). COX-1 activity appears to be related to "constitutive" or "housekeeping" functions in the gastric mucosa, kidney and platelets.
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Cyclooxygenase-2 and Nitric Oxide
Journal of Cardiovascular Pharmacology, 2006Nitric oxide (NO) is a simple but pluripotent molecule that is mainly released from vascular endothelial cells where it is formed intracellularly by nitric oxide synthase from L-arginine in response to several stimuli, including shear stress or muscarinic receptor stimulation. NO stimulates guanylyl cyclase to form cyclic guanosine monophosphate, which
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Regulation of cyclooxygenase activity by metamizol.
European Journal of Pharmacology, 1999Federico Gago, Susana Alemany, P Ortiz
exaly
Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
FEBS Letters, 1993Anthony W Ford-Hutchinson, G P O'Neill
exaly
Compensatory Prostaglandin E2 Biosynthesis in Cyclooxygenase 1 or 2 Null Cells
Journal of Experimental Medicine, 1998Takuro Kanekura +2 more
exaly