Results 81 to 90 of about 24,541,782 (296)
Study of molecular simulation Cyclooxygenase-1 and Cyclooxygenase-2 Inhibitors
, 2009 [[abstract]]In this study, molecular simulations are used to search COX-1 and COX-2 inhibitors. The cyclooxygenase in the mammal mainly has two different isoforms that are COX-1 and COX-2.
Pin-chen Liu
core
Antiproliferative Benzoindazolequinones as Potential Cyclooxygenase-2 Inhibitors
Molecules, 2019 Quinones and nitrogen heterocyclic moieties have been recognized as important pharmacophores in the development of antitumor agents. This study aimed to establish whether there was any correlation between the in silico predicted parameters and the in ...
Aurora Molinari +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Difference in cyclooxygenase-2 (cox-2) expression between low and high grade papillary carcinoma in human bladder cancer [PDF]
, 2008 The objective of this study was to improve the estimation of the prognostic behavior by difference of cyclooxygenase-2 (COX-2) expression between low and high grade papillary carcinoma of human transitional cell bladder cancer.
Sunarjo Hardjowijoto, NIDN. 9900981294 +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Cyclooxygenase-2 in prostate cancer
, 2000 Prostate cancer (pc) is the most commonly diagnosed adenocarcinoma and the second leading cause of cancer death after lung cancer in men in the Western world.
Madaan, S., Lalani, E-N., Abel, P. D.
core
Cyclooxygenase-2 (COX-2) Expression in Equine Melanocytic Tumors
Veterinary SciencesEquine melanocytic tumors are common and have an unusual benign behavior with low invasiveness and metastatic rates. However, tumoral mass growth is usually a concern that can have life-threatening consequences. COX-2 is related to oncogenesis, promoting
José Pimenta +3 more
doaj +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Cyclooxygenase 2 (COX-2) inhibitors
, 2022 Ciklooksigenaza-2 (engl. Cyclooxygenase-2, COX-2) je enzim koji se pojavljuje u bolnim i upaljenim tkivima, dok je u zdravim tkivima uglavnom neaktivan.
Magić, Dina
core +2 more sources