Results 291 to 300 of about 231,004 (334)

Biological evaluation and molecular Docking studies of the prepared chalcone derivatives as potential anti-Alzheimer agents. [PDF]

Sci Rep
Agbo EN, Maluleke BK, Gildenhuys S, Leboho TC, Nxumalo W.   +4 more
europepmc   +1 more source

Influence of Available Hydrophobic Interactions in New 2‑(Propylthio)‑<i>N</i>‑(1,3,4-thiadiazol-2-yl)nicotinamide Pharmacophore and Evaluation of Its Therapeutic Potential. [PDF]

ACS Omega
Nachimuthu L, Desikan R.
europepmc   +1 more source

Analgesic and anti-inflammatory potential of Ficus Palmata Forssk.: an In-vitro and In-vivo approach. [PDF]

Sci Rep
Al-Qahtani J, Fatima Z, Aati HY, Ghalloo BA, Al-Taweel A, Al-Yami K, Sajid-Ur-Rehman M, Al-Enezi B, Zubair HM, Khan KU.   +9 more
europepmc   +1 more source

Effect of cyclooxygenase (COX)-2 activation on diabetic neuropathy

, 2008
Aaron P. Kellogg
openalex   +1 more source

Exploring the Correlation between Immunohistochemical Findings and Bile Constituents in Choledochal Malformation Specimens.

J Indian Assoc Pediatr Surg
Goswami C, Yadav R, Kakkar A, Prakash S, Agarwala S, Verma A.   +5 more
europepmc   +1 more source

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Cyclooxygenase Assays

Current Protocols in Pharmacology, 1998
AbstractCyclooxygenase (COX, also known as prostaglandin H2 synthase, PGH2) is one of the most significant enzymes in pharmacology since COX inhibition is the mechanism of action of most nonsteroidal anti‐inflammatory drugs (NSAIDs). There are two forms: COX‐1 is a constitutive form of the enzyme that has been linked to the production of ...
J K, Gierse, C M, Koboldt
openaire   +2 more sources

Cyclooxygenase‐independent actions of cyclooxygenase inhibitors

The FASEB Journal, 2001
Several studies have demonstrated unequivocally that certain nonsteroidal anti‐inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and flurbiprofen cause anti‐inflammatory and antiproliferative effects independent of cyclooxy‐genase activity and prostaglandin synthesis inhibition.
I, Tegeder, J, Pfeilschifter, G, Geisslinger   +2 more
openaire   +2 more sources

Cyclooxygenase mechanisms

Current Opinion in Chemical Biology, 2000
Several advances have occurred in the past year in our understanding of cyclooxygenase catalysis. The role of specific heme oxidation states in the formation of catalytically competent tyrosyl radicals has been defined; the identity of physiological hydroperoxide activators has been established; and the participation of individual amino acids in ...
openaire   +2 more sources