Results 291 to 300 of about 221,688 (338)

Effect of Synthetic Peptides Identified in the Bullfrog Skin on Inflammation and Oxidative Stress Control: An In Vitro Analysis. [PDF]

Molecules
Pelinsari SM, Mattosinhos PDS, Dias MMDS, de Paula RA, Novaes RD, Vilela EF, Valacchi G, Gonçalves RV.   +7 more
europepmc   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

The CXCL10‐CXCR3 Axis Induces Tumor‐Associated Neutrophils to Interfere with CTLs‐Mediated Antitumor Activity in EBV‐Associated Epithelial Cancers

Advanced Science, EarlyView.
Compared with EBV‐negative epithelial cancer cells, EBV‐associated epithelial cancer cells exhibit enhanced secretion of chemokines, including CXCL10 and CCL5, to attract neutrophils. Via the CXCL10‐CXCR3 axis‐mediated positive feedback loop, neutrophils within EBV‐associated epithelial cancer cells are induced to form abundant NETs, which facilitate ...
Dijun Ouyang, Tong Xiang, Yuanyuan Chen, Mengjia Song, Jingjing Zhao, Hao Chen, Si Li, Lifeng Zhang, Chi Xu, Yan Ren, Yong Tao, Qijing Wang, Jia He, Yongqiang Li, Sisi Xie, Yuanyuan Liu, Yan Wang, Xinyi Yang, Jinqi You, Songzuo Xie, Yingzi Li, Desheng Weng, Qiuzhong Pan, Qi Yang, Jianchuan Xia   +24 more
wiley   +1 more source

CKD in a Young Man with Nephrogenic Diabetes Insipidus. [PDF]

Kidney360
Teitelbaum I.
europepmc   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

Novel Benzenesulfonamide Derivatives of 5'-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation Using a Rat Model of Carrageenan-Induced Paw Edema. [PDF]

Biomedicines
Hamed AM, Enaili SS, I Mohammed W, Abouelella AMA, Mohana ZEE, Monir DM, Soliman SS, Hamouda EEM, Elatif HMA, El-Saghier AM.   +9 more
europepmc   +1 more source

Phytochemical analysis and neuroprotective potential of Achillea santolina L. fractions. [PDF]

Sci Rep
Abdel-Baki PM, Mahdy NE, Ibrahim RM, El Badawy SA, Ali SE, Ibrahim MA, Khattab MS, El-Rashedy AA, Emam SR.   +8 more
europepmc   +1 more source

Incidence rates of tuberculosis and inflammatory bowel disease in patients with ankylosing spondylitis treated with biologics in Korea. [PDF]

Rheumatology (Oxford)
Kwon OC, Lee HS, Yang J, Paul T, Jin H, Lee Y, Park MC.   +6 more
europepmc   +1 more source

Anticancer and Anti-Inflammatory Effects of Benzothiazole Derivatives Targeting NF-κB/COX-2/iNOS in a Hepatocellular Carcinoma Cell Line. [PDF]

Turk J Pharm Sci
Üremiş MM, Üremiş N, Ceylan M, Türköz Y.   +3 more
europepmc   +1 more source