Results 111 to 120 of about 128,590 (304)

Neuroprotective activity of Leontice leontopetalum extract against H2O2-stimulated oxidative stress in PC12 cells [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: Neuronal toxicity can be induced by oxidative stress via free radicals production. In recent years, great interest has been expressed to the traditional and herbal medicines.
S. Sahranavard*   +3 more
doaj  

Immunohistochemical expression of Cyclooxygenase-2 in colorectal carcinoma and its association with clinicopathological parameters

open access: yesZanco Journal of Medical Sciences, 2019
Background and objective: Inflammatory process and genetic factors play a key role in neoplasia of colorectal cancer. Cyclooxygenase-2 is involved in a variety of important cellular functions, including cell growth and differentiation, cancer cell ...
Payman MS. Salim   +2 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Cyclooxygenase Inhibitors Affect Recovery of Ischemic-injured Jejunum [PDF]

open access: yes, 2005
he cyclooxygenase (COX) enzyme produces prostaglandins. There are 3 isoforms of COX (including COX-1 and COX-2). As prostaglandins are involved in intestinal repair, the objective of this study was to examine the effects of COX inhibitors on healing of ...
Tomlinson, Julia Elizabeth
core  

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi   +8 more
wiley   +1 more source

Difference in cyclooxygenase-2 (cox-2) expression between low and high grade papillary carcinoma in human bladder cancer [PDF]

open access: yes, 2008
The objective of this study was to improve the estimation of the prognostic behavior by difference of cyclooxygenase-2 (COX-2) expression between low and high grade papillary carcinoma of human transitional cell bladder cancer.
Sunarjo Hardjowijoto, NIDN. 9900981294   +3 more
core  

Comparison of cyclooxygenase-2 expression. [PDF]

open access: yes, 2014
1–5: control group; 6–10: inflamed group. Intraprostatic injection of carrageenan induced significant increase of cyclooxygenase-2(COX2) expression at 24 h, 7d and 14d after injection.
Xiongbing Zu (440064)   +12 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Overexpression of cyclooxygenase-2 correlates with chromosomal gain at the cyclooxygenase-2 locus and decreased patient survival in advanced colorectal carcinomas [PDF]

open access: yes, 2004
PURPOSE: Overexpression of cyclooxygenase-2 is observed in a variety of malignancies including colorectal cancer. However, to date, cyclooxygenase-2 expression by advanced human colorectal cancers and their metastases has been poorly characterized.
Schluns, K.   +7 more
core   +1 more source

Cyclo-Oxygenase 2 Modulates Chemoresistance in Breast Cancer Cells Involving NF-κB

open access: yesCellular Oncology, 2009
Background: Breast cancer cells can develop chemoresistance after prolonged exposure to cytotoxic drugs due to expression of the multi drug resistance (MDR) 1 gene.
Maria Chiara Zatelli   +5 more
doaj   +1 more source

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