Results 241 to 250 of about 995,042 (360)

Andrographolide Reduces Cytokine Release and Cyclooxygenase-2 Expression by Inhibiting the JNK and NF-κB Pathways in Glioblastoma Cells Exposed to Cadmium

Thitima Kasemsuk, Pornpun Vivithanaporn, Pichsinee Woonfak, Phisit Khemawoot   +3 more
openalex   +2 more sources

Successful Treatment With Meloxicam, a Cyclooxygenase-2 Inhibitor, of Patients With Extra-Abdominal Desmoid Tumors: A Pilot Study [PDF]

, 2009
Yoshihiro Nishida, Satoshi Tsukushi, Yoji Shido, Junji Wasa, Naoki Ishiguro, Yoshihisa Yamada   +5 more
openalex   +1 more source

Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma [PDF]

, 2017
Das, Sunit, Dhand, Karan, Guan, Jennifer, Gunter, Simon, Kim, Albert, Li, Chris, Morshead, Cindi, Ng, Sheena, Nusrat, Labeeba, Wu, Megan   +9 more
core   +3 more sources

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. [PDF]

ACS Chem Biol, 2016
Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ.   +7 more
europepmc   +1 more source

Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: Efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects [PDF]

, 1998
Lee S. Simon, Frank L. Lanza, Peter E. Lipsky, Richard C. Hubbard, Sheela Talwalker, Benjamin D. Schwartz, Peter C. Isakson, Gilbert Geis   +7 more
openalex   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Einfluß des Cyclooxygenase-2-Inhibitors NS-398 auf Proliferation und Apoptose von Ovarialkarzinomzellinien

, 2005
Antje Fürstenberg
openalex   +2 more sources

Gastrointestinal tract perforation in dogs treated with a selective cyclooxygenase-2 inhibitor: 29 cases (2002–2003) [PDF]

, 2005
B. Duncan X. Lascelles, Anthony T. Blikslager, Steven M. Fox, Doug Reece   +3 more
openalex   +1 more source