Results 251 to 260 of about 995,042 (360)

In Vitro Effects of VA441, a New Selective Cyclooxygenase-2 Inhibitor, on Human Osteoarthritic Chondrocytes exposed to IL-1^|^beta;

, 2012
Antonella Fioravanti, Laura Tinti, Nicola Antonio Pascarelli, Angela Di Capua, Antonello Lamboglia, Andrea Cappelli, Mariangela Biava, Antonio Giordani, S. Niccolini, Mauro Galeazzi, Maurizio Anzini   +10 more
openalex   +2 more sources

Combined Inhibitory Effects of Green Tea Polyphenols and Selective Cyclooxygenase-2 Inhibitors on the Growth of Human Prostate Cancer Cells Both In vitro and In vivo

Clinical Cancer Research, 2007
V. Adhami, A. Malik, Najia Zaman, S. Sarfaraz, I. Siddiqui, D. Syed, F. Afaq, Farrukh Sierre Pasha, M. Saleem, H. Mukhtar   +9 more
semanticscholar   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Synthesis and Structure−Activity Relationship Studies of 1,3-Diarylprop-2-yn-1-ones:  Dual Inhibitors of Cyclooxygenases and Lipoxygenases

, 2006
Praveen P. N. Rao, Qiao‐Hong Chen, Edward E. Knaus   +2 more
openalex   +1 more source

Aspirin versus cyclooxygenase-2 inhibitors as quorum sensing inhibitors of Pseudomonas aeruginosa [PDF]

, 2018
A Abdelfattah El Sayed, Walaa Abdel-Latif, A Ahmad Nabil A. Algammal   +2 more
openalex   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

Journal of Neurochemistry, 2003
P. Klivényi, M. Kiaei, G. Gárdián, N. Calingasan, M. Beal   +4 more
semanticscholar   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Structure–activity relationship of novel series of 1,5-disubstituted tetrazoles as cyclooxygenase-2 inhibitors: Design, synthesis, bioassay screening and molecular docking studies

, 2016
Baker Jawabrah Al‐Hourani, Wajdy Al‐Awaida, Khalid Z. Matalka, Musa I. El‐Barghouthi, Fatima Alsoubani, Frank Wuest   +5 more
openalex   +1 more source