Results 301 to 310 of about 995,042 (360)

Decoding intratumoral cyclooxygenase-2 signaling through multi-omics: insights from esophageal cancer and beyond. [PDF]

Clin Exp Med
Zhuang XY, Xu DM, Chen JN, Huang XY, Wu SP, Zhang YF, He XH.   +6 more
europepmc   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Balancing Pain Relief and Safety: Gastrointestinal and Cardiovascular Risk Assessment in Nonsteroidal Anti-Inflammatory Drug Users and the Role of Gastroprotective Co-Therapy. [PDF]

Pharmaceuticals (Basel)
Shareef J, Sridhar SB, Saeed ZM, Alsereidi AMR.   +3 more
europepmc   +1 more source

Efficacy and Safety of Paracetamol and NSAIDs for Fever and Pain Management in Children with Chronic Diseases: A Narrative Review. [PDF]

Children (Basel)
Milani GP, Nicolini G, Cananzi M, Spiezia L, Vidal E.   +4 more
europepmc   +1 more source

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives. [PDF]

Sci Rep
Rahman M, Zafar R, Jan MS, Darwish HW, Khattak H, Aschner M, Daglia M, Khan H.   +7 more
europepmc   +1 more source

Region-Specific Roles of TGF-β2 and Angiotensin II in Fibrotic and Inflammatory Remodeling of the Optic Nerve Head. [PDF]

Cells
Oh SE, Kim JH, Park SE, Park CK, Park HL.   +4 more
europepmc   +1 more source

Mechanisms of Pilocarpine-Induced Nitric Oxide and Prostaglandin Production in Porcine Ciliary Muscle. [PDF]

FASEB Bioadv
Benozzi G, Quinteros Villarruel E, Zuluaga AF, Orman B.   +3 more
europepmc   +1 more source

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Cyclooxygenase-2 inhibitors

Current Opinion in Internal Medicine, 2006
The purpose of this review is to summarize new information regarding the use of selective inhibitors of the cyclooxygenase-2 enzyme, emphasizing recent developments regarding cardiovascular risk.Selective cyclooxygenase-2 inhibitors are as effective as nonselective nonsteroidal antiinflammatory drugs in relieving pain and inflammation but are ...
Christopher J, Hawkey, Paul J, Fortun
  +5 more sources

Cyclooxygenase-2 Inhibitors

Current Pharmaceutical Design, 1995
Prostaglandins are synthesized by the enzyme cyclooxygenase (COX), which is the target for nonsteroidal anti-inflammatory drugs (NSAIDs). Recently a second form of COX was discovered (COX-2) that is induced by inflammatory stimuli. The identification of an inducible form of COX led to the hypothesis that COX-2 is responsible for inflammatory ...
David B. Reitz, Peter C. Isakson
openaire   +1 more source