Results 111 to 120 of about 154,825 (291)

An Enhanced Metabolization Protocol for In Vitro Genotoxicity Assessment of N‐Nitrosamines in Mammalian Cells

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT N‐Nitrosamines (NAs) are probable human carcinogens and were detected as impurities in pharmaceuticals, which led to a concern for human health. NAs require metabolic activation before they become mutagenic, and not all NAs are mutagenic since their reactivity is related to their structure.
M. E. Geijer   +4 more
wiley   +1 more source

The use of steroids in adult epilepsy: A systematic review

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The objective of this study is to systematically review the clinical studies investigating the use of steroids in adult epilepsy. Methods This systematic review utilized Preferred Reporting Items for Systematic Review and Meta‐analysis Protocols (PRISMA‐P) to examine literature on the use of steroids in adult epilepsy.
Ruth Walsh   +2 more
wiley   +1 more source

Clinical evaluation of a new alkylating agent: Cytoxan (cyclophosphamide) [PDF]

open access: bronze, 1960
Peter R. Coggins   +2 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience

open access: yesPediatric Blood &Cancer, Volume 70, Issue 2, February 2023., 2023
Abstract Malignant ectomesenchymoma (MEM) is an extremely rare soft tissue tumor typical of young children, currently included in the category of skeletal muscle malignancies and characterized by a neuroblastic component. This study describes a series of 10 patients prospectively registered in the European paediatric Soft tissue sarcoma Study Group ...
Giuseppe Maria Milano   +11 more
wiley   +1 more source

Anti‐GAD65 musicogenic epilepsy: Bilateral and independent mesial temporal seizures revealed by foramen ovale electrodes

open access: yesEpilepsia Open, EarlyView.
Abstract Musicogenic epilepsy (ME) is characterized by seizures triggered by music. The epileptogenic focus in this rare reflex epilepsy is often in the temporal lobe, although the precise localization is still unclear. A correlation between ME and the presence of GAD65 antibodies indicates a potential immunological pathogenic mechanism. We evaluated a
Roberta Di Giacomo   +17 more
wiley   +1 more source

Structural Characterization, Phenolic Acid Modification, and Antioxidant Activities of Polysaccharide From Mogroside Waste Liquid of Siraitia grosvenorii

open access: yesFood Frontiers, EarlyView.
ABSTRACT To improve the comprehensive utilization of Siraitia grosvenorii (Swingle) C. Jeffrey, a novel polysaccharide (SGP) was isolated from the mogroside waste liquid of S. grosvenorii. In addition, ferulic acid–SGP (FA‐SGP) and caffeic acid–SGP (CA‐SGP) were prepared by modifying SGP with phenolic acid.
Jiajing Duan   +6 more
wiley   +1 more source

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