Results 71 to 80 of about 257,683 (336)
Advanced Science, EarlyView.This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu +7 more
wiley +1 more source
Protective effects of Spirulina (Arthrospira Platensis) on In Vitro Fertilization (IVF) and embryo development in female mice treated with cyclophosphamide [PDF]
Journal of Advanced Biomedical Sciences, 2018 Background & objective: Cyclophosphamide is an extensively used chemotherapeutic agent against wide varieties of neoplastic ailments, which has been known to cause ovarian damages and infertility in mammals.
Golchin Mousavi +3 more
doaj
Myocarditis with Cardiac Failure: Initial Manifestation of Systemic Lupus Erythematosus [PDF]
Journal of Clinical and Diagnostic Research, 2019 Cardiac involvement is very rare in Systemic Lupus Erythematosus (SLE). Pericarditis is the leading cardiovascular manifestation in SLE followed by endocarditis, conduction abnormality, coronary artery disease and myocardial dysfunction.
Suchi Acharya +3 more
doaj +1 more source
Advanced Science, EarlyView.This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan +6 more
wiley +1 more source
Advanced Science, EarlyView.In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang +10 more
wiley +1 more source
Geraniol alleviates cyclophosphamide-induced cardiotoxicity in mice
Asian Pacific Journal of Tropical BiomedicineObjective: To explore the effect of geraniol on cyclophosphamide- induced cardiotoxicity. Methods: Mice were divided into five groups: the control group, the cyclophosphamide group (200 mg/kg cyclophosphamide, i.p.
Shahid Karim, Rasheed A. Shaik
doaj +1 more source
Annals of the Rheumatic Diseases, 2015 OBJECTIVES The RITUXVAS trial reported similar remission induction rates and safety between rituximab and cyclophosphamide based regimens for antineutrophil cytoplasm antibody (ANCA)-associated vasculitis at 12 months; however, immunosuppression ...
R. Jones +13 more
semanticscholar +1 more source
CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
Advanced Science, EarlyView.This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou +15 more
wiley +1 more source
Journal of Clinical Oncology, 2012 PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).
N. Johnson +30 more
semanticscholar +1 more source
Role of metabolites of cyclophosphamide in cardiotoxicity
BMC Research Notes, 2017 The dose-limiting toxic effect of cyclophosphamide (CY) is cardiotoxicity. The pathogenesis of myocardial damage is poorly understood, and there is no established means of prevention.
K. Kurauchi +4 more
semanticscholar +1 more source