Results 61 to 70 of about 175,213 (250)

Evaluation of effect of tribulus terrestris extract on sex hormones in male rats after treatment with cyclophosphamide

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2014
Introduction: Cyclophosphamide, anti-cancer drugs which are used in chemotherapy. Purpose of this study was to investigate the effects of Tribulus terrestris extract on sex hormones in male rats after treatment with cyclophosphamide. material and Method:
najme rajabi, hojatollah karimi jashni
doaj  

A descriptive study to analyze chemotherapy-induced hair loss and its psychosocial impact in adults: Our experience from a tertiary care hospital

open access: yesIndian Dermatology Online Journal, 2019
Background: Hair loss is one of the most commonly reported and psychologically distressing adverse effects of chemotherapeutic agents. Studies on its impact on psychosocial aspect of cancer patients are lacking at present.
Neerja Saraswat   +4 more
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa   +3 more
wiley   +1 more source

Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin

open access: yesOman Journal of Ophthalmology
This study outlines a scenario involving unilateral periocular inflammation exhibited resistance to conventional immunomodulatory therapy (IMT) and biologic response modifying agents, which was successfully managed with oral cyclophosphamide monotherapy.
Arash Maleki   +3 more
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

open access: yesArthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet   +11 more
wiley   +1 more source

Primary Central Nervous System Angiitis Mimicking a Space-Occupying Lesion

open access: yesIndian Journal of Neurosurgery
Background and Purpose Intracranial space-occupying lesions are a sine qua non for neoplastic lesions; however, occasionally non-neoplastic lesions mimic neoplastic lesions, leading to diagnostic dilemmas.
Edmond Jonathan Gandham   +3 more
doaj   +1 more source

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian   +7 more
wiley   +1 more source

Protective Effects of Galbanum Essential Oil on Histomorphometric Changes in Placenta of Cyclophosphamide Treated Rat

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016
BACKGROUND AND OBJECTIVE: Cyclophosphamide is a drug widely used to treat cancer, skin diseases and immune system disorders. Since cyclophosphamide passes placenta during pregnancy and causes disorders in fetus, this study was conducted to assess the ...
Z Rezaei   +3 more
doaj  

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Hydrogen sulfide and ferroptosis inhibition underlies the dietary restriction-induced protection against cyclophosphamide cystitis

open access: yesFrontiers in Pharmacology
Dietary restriction (DR) has emerged as a potential therapeutic intervention for various pathological conditions. This study investigated the effects of DR on cyclophosphamide-induced cystitis in mice.
Zhimin Mao   +5 more
doaj   +1 more source

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