Results 111 to 120 of about 86,527 (148)
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Transplantation Proceedings, 2004
Six hundred thirty-eight cadaveric kidney transplant patients between 1983 and 2001 were treated with cyclosporine (CsA) for 87 +/- 58 months. Among 571 patients with follow-up greater than 12 months, the 15-year renal function was investigated to assess the probability of a >30% increase in serum creatinine (sCr) above the month-6 value (baseline) and
SANDRINI S +12 more
+16 more sources
Six hundred thirty-eight cadaveric kidney transplant patients between 1983 and 2001 were treated with cyclosporine (CsA) for 87 +/- 58 months. Among 571 patients with follow-up greater than 12 months, the 15-year renal function was investigated to assess the probability of a >30% increase in serum creatinine (sCr) above the month-6 value (baseline) and
SANDRINI S +12 more
+16 more sources
Drug Intelligence & Clinical Pharmacy, 1985
Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
openaire +2 more sources
Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
openaire +2 more sources
Southern Medical Journal, 1986
Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
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Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
openaire +2 more sources
Journal of the American Academy of Dermatology, 1986
Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's ...
E H, Page, D M, Wexler, L C, Guenther
openaire +2 more sources
Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's ...
E H, Page, D M, Wexler, L C, Guenther
openaire +2 more sources
Cyclosporine and Prostaglandins
Annals of Internal Medicine, 1985Excerpt To the editor: Cyclosporine and its nephrotoxicity have recently been reviewed in your journal (1). Subsequently, Dr.
J. Michael +4 more
openaire +3 more sources
Folia Microbiologica, 1995
This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to ...
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This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to ...
openaire +2 more sources
Annals of Internal Medicine, 1987
Excerpt To the editor: Graves disease with ophthalmopathy was diagnosed in a 37-year-old woman. Treatment consisted of propranolol, 20 mg three times a day, propylthiouracil, 100 mg three times a d...
Noppen, Marc +4 more
openaire +3 more sources
Excerpt To the editor: Graves disease with ophthalmopathy was diagnosed in a 37-year-old woman. Treatment consisted of propranolol, 20 mg three times a day, propylthiouracil, 100 mg three times a d...
Noppen, Marc +4 more
openaire +3 more sources
Cyclosporine is angiostatic [PDF]
Experientia, 1992 The systemic effect of the immunosuppressive drug cyclosporine (CS) on formation of new blood vessels was studied quantitatively in rats using the mesenteric-window assay. Angiogenesis was induced by i.p. injection of saline. CS at a s.c. dose of 4 mg/kg/day, which is in the range used clinically, suppressed angiogenesis (inhibiting branching or ...
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Journal of the American Academy of Dermatology, 1989
Cyclosporine is a potent immunosuppressive agent with no appreciable effect on the bone marrow and a selective inhibitory effect on helper T cells. Oral cyclosporine was first used to prevent organ rejection but also has been reported to be effective in other disorders. In cutaneous diseases that respond to oral cyclosporine helper T cells appear to be
Leslie L. Rocher +7 more
openaire +3 more sources
Cyclosporine is a potent immunosuppressive agent with no appreciable effect on the bone marrow and a selective inhibitory effect on helper T cells. Oral cyclosporine was first used to prevent organ rejection but also has been reported to be effective in other disorders. In cutaneous diseases that respond to oral cyclosporine helper T cells appear to be
Leslie L. Rocher +7 more
openaire +3 more sources