Results 91 to 100 of about 102,207 (305)

The sodium retaining effects of cyclosporine [PDF]

, 1992
The sodium retaining effects of cyclosporine. The effect of chronic cyclosporine administration on volume regulation was studied in mongrel dogs. Dogs received either cyclosporine (20 mg/kg/day p.o.; N = 7) or vehicle (N = 6) while being maintained on a ...
Heublein, Denise M., Sandberg, Sharon M., Lloyd, Margaret A., Ciresi, David L., Edwards, Brooks S.   +4 more
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Neuroprotective effects of cyclosporine A and GluR2 AMPA receptors against excitotoxicity in FVB/N and C57BL/6 mice

, 2015
Glutamate (Glu) is an important excitatory neurotransmitter in the brain. It\ud binds to ionotropic Glu receptors located in the postsynaptic membrane and allows\ud calcium into the cell. Abnormally high levels of Glu can induce excitotoxicity (seizure),\
Chin-Curtis, Alena
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Structure of Cyclosporine and Its Metabolites: Total Synthesis of Cyclosporine Metabolites Formed by Oxidation at Positions 4 and 9 of Cyclosporine. Preparation of Leucine-4-cyclosporine, (γ-Hydroxy)-N-methyl-leucine-9-cyclosporine and Leucine-4-(γ-hydroxy)-N-methyl-leucine-9-cyclosporine

, 1992
The syntheses of the cyclosporine metabolites Leu-4-cyclosporine (AM4N), (γ-OH)MeLeu-9-cyclosporine (AM9) and Leu-4-(γ-OH)MeLeu-cyclosporine (AM4N9) were completed.
Wenger, Roland M., Timbers, Charles, Martin, Kurt, Tromelin, Anne   +3 more
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Solubility Studies of Cyclosporine Using Ionic Liquids

, 2019
Six ionic liquids (ILs) were selected based on their chemical and physical properties to study the solubility of cyclosporine A. Of these, cyclosporine exhibited higher room temperature solubility in 1-ethyl-3-methylimidazolium acetate ([C(2)mim][OAc ...
Paula Berton, Robin D. Rogers, Choudhary, Hemant, Mishra, Manish Kumar, Rogers, Robin D., Allan S. Myerson, Berton, Paula, Manish Kumar Mishra, Hemant Choudhary, Myerson, Allan S.   +9 more
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Cyclosporine-Based Medicinal Products: A Comparative Analysis of Pharmacopeial Quality Requirements

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Cyclosporine is an immunosuppressive agent used in organ trans plantation, for the treatment of autoimmune diseases, and also in ophthalmology. Cyclosporine-based medicinal products (MPs) are registered in the Russian Fede ration in various
A. N. Novichenko, V. V. Akopova, P. A. Onisko   +2 more
doaj   +1 more source

Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group

Haematologica, 2008
Large granular lymphocyte leukemia-associated pure red cell aplasia accounts for a significant portion of secondary pure red cell aplasia cases. However, because of its rarity, long-term responses and relapse rates after immunosuppressive therapy are ...
Naohito Fujishima, Ken-ichi Sawada, Makoto Hirokawa, Kazuo Oshimi, Koichi Sugimoto, Akira Matsuda, Masanao Teramura, Masamitsu Karasawa, Ayako Arai, Yuji Yonemura, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, Keiya Ozawa   +13 more
doaj   +1 more source

A meta-analysis of cyclosporine treatment for Stevens–Johnson syndrome/toxic epidermal necrolysis

, 2018
Qin Xiang Ng,1,2 Michelle Lee Zhi Qing De Deyn,3 Nandini Venkatanarayanan,4 Collin Yih Xian Ho,2 Wee-Song Yeo,5 1Department of Medicine, National University Hospital, National University Health System, Singapore; 2MOH Holdings Pte Ltd, Singapore ...
Ho CYX, Ng QX, Venkatanarayanan N, Yeo WS, De Deyn MLZQ   +4 more
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Morphology of ischemic acute renal failure, normal function, and cyclosporine toxicity in cyclosporine-treated renal allograft recipients [PDF]

, 1993
Morphology of ischemic acute renal failure, normal function, and cyclosporine toxicity in cyclosporine-treated renal allograft recipients. To characterize morphologic changes in the early post-transplant period in cyclosporine-treated renal allograft ...
Marcussen, Niels, Slatnik, Irena, Keown, Paul, Racusen, Lorraine C., Olsen, Steen, Solez, Kim, Burdick, James F.   +6 more
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Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial

BMC Medicine
Background Calcineurin inhibitors, such as cyclosporine, are primary treatments for membranous nephropathy (MN). Optimizing this regimen is crucial to reduce nephrotoxicity and enhance immunological remission.
Fang Wang, Chao Yang, Yue Shu, Cai-xia Lin, Yao Yao, Yue Li, Yi-miao Zhang, Xin Wang, Li-qiang Meng, Xu-yang Cheng, Gang Liu, Ming-hui Zhao, Zhao Cui   +12 more
doaj   +1 more source

Neoral: A Microemulsion Cyclosporine

, 1996
Cyclosporine (Sandimmune), introduced in the 1980s, improved patient and graft survival rates primarily by decreasing the frequency and severity of early, acute rejection.
David I Min
core   +1 more source