Results 111 to 120 of about 142,539 (313)

Efficacy of Lebrikizumab in Patients With Severe Atopic Dermatitis Who Would be Eligible for Treatment Based on the South Korean Reimbursement Criteria

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lebrikizumab is approved to treat patients with moderate‐to‐severe atopic dermatitis (AD). Objectives This study evaluated the 16‐week efficacy outcomes of lebrikizumab in adults and adolescents with severe AD in ADvocate trials who would be eligible for treatment based on South Korean reimbursement‐like criteria. Methods This was a
Chong Hyun Won, Chun Wook Park, Jiyoung Ahn, Joo Yeon Ko, Sang Hyun Cho, Yang Won Lee, Joo Hee Lee, Khai Jing Ng, Min Young Hong, Jinglin Zhong, Martin Dossenbach, Sang Wook Son   +11 more
wiley   +1 more source

CASE STUDY OF USING THE DOMESTIC ANALOGUE OF CYCLOSPORINE A

Педиатрическая фармакология, 2010
The article illustrates results of an important trial for the Russian pharmaceutical industry, an assessment of the efficacy and safety of domestic immunosuppressive medication Cyclosporine A. A comparative analysis was made of pharmacokinetics, hepato-,
V.A. Goryainov, M.M. Kaabak, N.N. Babenko, N.T. Vorob'eva, L.A. Shishlo, M.M. Morozova, T.Yu. Cheprasova   +6 more
doaj   +2 more sources

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni, Francois Rosset, Isotta Giunipero di Corteranzo, Lorenzo Bellando, Rebecca Senetta, Simone Ribero, Pietro Quaglino   +6 more
wiley   +1 more source

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

The Effect of Cyclosporine and Tacrolimus Systemic Therapy on Gingival Overgrowth in Renal Transplant Patients Aged Between 18-70 Years in Erbil City-Iraq

Erbil Dental Journal
Background: Gingival overgrowth has been linked to systemic therapy with Cyclosporine and Tacrolimus in Renal transplanted cases. Aim: The prevalence and characteristics of gingival overgrowth and periodontal treatment will be examined in patients ...
Aveen A. Jalal
doaj   +1 more source

Pyoderma Gangrenosum: A Retrospective Cohort Study of Comorbidities and Therapies in Over 65,000 Patients in the TriNetX Database

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange, Tara Sholji, Marra Aghajani, Cindy Kok, John Frew   +4 more
wiley   +1 more source

Triacylglycerol‐Based Insulin Resistance Indices and Post‐Transplantation Diabetes Mellitus After Liver Transplantation

Lipids, EarlyView.
ABSTRACT Background: Post‐transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol‐glucose product (TyG) and the triacylglycerol‐to‐high‐density lipoprotein (HDL) cholesterol ratio (TAG/HDL‐c) are indices that can serve as triacylglycerol‐based proxies for ...
Mateo Chvatal‐Medina, Yakun Li, Adrian Post, Margery A. Connelly, Han Moshage, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart, on behalf of TransplantLines investigators   +9 more
wiley   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis (DIG‐MG): A Randomized Controlled Trial of Feasibility, Adherence, and Effects on Fatigue

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Physical activity and sleep influence fatigue in myasthenia gravis (MG), and digital health technologies (DHT) enable objective monitoring of these behaviors in daily life. Using this approach, we evaluated whether a lifestyle intervention targeting physical activity or sleep hygiene could reduce fatigue in MG.
Maja Norling, Niclas Eriksson, Elisabet Westerberg, Ingela Nygren, Klara Norman, Julia Hedberg, Sui H. Wong, Susanna Jernelöv, Pernilla Åsenlöf, Anna Rostedt Punga   +9 more
wiley   +1 more source

Early and late outcomes after heart transplantation in a low-volume transplant centre [PDF]

, 2012
Early (one year) and late (15 year) outcomes after heart transplantation in Malta were evaluated by means of a retrospective analysis of mortality and morbidity, derived from the transplant database.
Manche, Alexander
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