Results 71 to 80 of about 102,207 (305)
Enhanced Spontaneous Transmitter Release at Murine Motor Nerve Terminals with Cyclosporine
, 2009 Cyclosporine, a calcineurin inhibitor, significantly enhances spontaneous acetylcholine release after a brief tetanus and potentiates the effect of phorbol 12,13- dibutyrate.
Lin, Min-Jon; Lin-Shiau, Shoei-Yn +1 more
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Cyclosporine : A review article [PDF]
, 2008 Cyclosporine is a immunosuppressive agent used in solid organ and bone marrow transplantation worldwide. Its discovery in 1972 was revolutionary in transplant medicine because of the need to suppress the immune system without affecting other cells ...
Eidet, Jon Roger, Ask, Andreas
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Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source
Frontiers in Pharmacology, 2018 There are various studies that have addressed the use of Cyclosporine among patients with acute myocardial infarction (AMI). However, to date there is hardly any concise and systematically structured evidence that debate on the efficacy and safety of ...
Firdaus A. Rahman +22 more
doaj +1 more source
The parameters of Cyclosporine A induced inhibition of a T cell dependent antibody response
, 1990 Cyclosporine A (CsA) is a widely used immunosuppressive drug which has novel, clinically beneficial effects on the immune system. Substantial evidence indicates that CsA acts preferentially by impairing T cell lymphokine production, but there is some ...
Schilke, Angela J.
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, 2006 The purpose of this study is the development of a quantification method to detect the amount of amorphous cyclosporine using Fourier transform infrared (FTIR) spectroscopy.
STRATTA, FABIO +3 more
core +1 more source
JPGN Reports, EarlyView.Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn +15 more
wiley +1 more source
فصلنامه دانشگاه علوم پزشکی جهرم, 2015 Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients Abstract: Background: Doppler ultrasonography is the best tool for assessment of transplanted kidneys’ vascular ...
zohreh makki +4 more
doaj
The effects of cyclosporine on drug metabolism in rats and its mechanism
, 2002 textImmunosuppressant cyclosporine (CsA) is primarily metabolized by cytochrome P450 3A (CYP3A), and a substrate for P-glycoprotein (P-gp). The large variability in CsA pharmacokinetics makes predicting CsA effects and toxicity difficult, which may be
Liu, Jingrong
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Journal of Surgical Oncology, EarlyView.ABSTRACT Liver transplantation (LT) is the definitive treatment for early hepatocellular carcinoma (HCC), based on established criteria. Pre‐transplant imaging occasionally underestimates the tumor burden or biological aggressiveness, leading to explant pathology that exceeds the projection criteria, such as Milan.
Serkan Sucu +2 more
wiley +1 more source