Results 61 to 70 of about 78,829 (264)

Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group

open access: yesHaematologica, 2008
Large granular lymphocyte leukemia-associated pure red cell aplasia accounts for a significant portion of secondary pure red cell aplasia cases. However, because of its rarity, long-term responses and relapse rates after immunosuppressive therapy are ...
Naohito Fujishima   +13 more
doaj   +1 more source

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To identify risk factors for abdominal pain and predictors of complicated abdominal pain in pediatric immunoglobulin A vasculitis (IgAV). Methods Retrospective multicenter study including children and adolescents (≤18 years) fulfilling the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization ...
Francisco Hugo Rodrigues Gomes   +14 more
wiley   +1 more source

Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2015
Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients Abstract: Background: Doppler ultrasonography is the best tool for assessment of transplanted kidneys’ vascular ...
zohreh makki   +4 more
doaj  

Cyclosporine is a potential curative treatment option for advanced thymoma

open access: yesExperimental Hematology & Oncology, 2017
Background Thymectomy can effectively cure most thymoma patients; however, patients with advanced thymoma typically require chemotherapy, which is associated with limited efficacy in this context.
Yusuke Isshiki   +3 more
doaj   +1 more source

Endoscopic findings in patients with Shwachman–Diamond syndrome: A report from the North American Shwachman–Diamond syndrome registry

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn   +15 more
wiley   +1 more source

Ciclosporina: riscos em idade pediátrica.

open access: yesActa Médica Portuguesa, 2010
Cyclosporine has been found to be effective and safe in many inflammatory skin disorders such as psoriasis and atopic dermatitis (AD), in adults and in children. Its use in paediatrics is still under scope.
João Antunes   +2 more
doaj   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak   +11 more
wiley   +1 more source

Relation of magnesium level to cyclosporine and metabolic complications in renal transplant recipients

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2009
Cyclosporine is the main immunosuppressive drug used for renal transplant reci-pients in order to prevent transplant rejection. Although the drug has increased the survival of patients and grafted organ, it has some side effects independent of its effect
Ahmadi Farrokhlagha   +2 more
doaj  

Pharmacokinetic Disposition Difference Between Cyclosporine and Voclosporin Drives Their Distinct Efficacy and Safety Profiles in Clinical Studies

open access: yesClinical Pharmacology: Advances and Applications, 2020
Yan Li,1 Maria Palmisano,1 Duxin Sun,2 Simon Zhou1 1Translational Development and Clinical Pharmacology, Celgene Corporation, Summit, NJ 07920, USA; 2Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109,
Li Y, Palmisano M, Sun D, Zhou S
doaj  

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni   +6 more
wiley   +1 more source

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