Results 221 to 230 of about 95,860 (291)

Cyclosporin ??? Allergan

Drugs in R & D, 2003
openaire   +2 more sources

Erythrokeratodermia‐Cardiomyopathy Syndrome: Expanding the DSP Mutational Spectrum Beyond Proline Substitutions

Pediatric Dermatology, EarlyView.
ABSTRACT Erythrokeratodermia cardiomyopathy (EKC) syndrome is a rare autosomal dominant disorder characterized by generalized erythrokeratoderma and progressive dilated cardiomyopathy, caused by pathogenic variants in the SR6 domain of desmoplakin (DSP).
Sepideh Hamzehlou, Ryland D. Mortlock, Caroline Echeandia‐Francis, Jing Zhou, Chao Xing, Nnenna G. Agim, Keith A. Choate, Donald A. Glass II   +7 more
wiley   +1 more source

Immunosuppressive Therapy in Pediatric Kidney Transplantation: Evolution, Current Practices, and Future Directions. [PDF]

Biomedicines
Al Riyami MS, Al Gaithi B, Al Kalbani N, Al Saidi S.   +3 more
europepmc   +1 more source

Antibody Serologies and Diagnostic Considerations in Reactive Infectious Mucocutaneous Eruption

Pediatric Dermatology, EarlyView.
ABSTRACT Reactive infectious mucocutaneous eruption (RIME) is an uncommon, post‐infectious mucocutaneous condition often associated with Mycoplasma pneumoniae, but which can be triggered by other pathogens. We retrospectively reviewed eight young adult patients diagnosed with RIME over a 10‐year period, all of whom had positive Mycoplasma pneumoniae ...
Aaron D. Smith, Olivia Cohen, Peter Jowdy, Catherine E. Lyons, Lauren Yi, Barrett Zlotoff   +5 more
wiley   +1 more source

A Rare Case of Extensive Oral Involvement in Bullous Systemic Lupus Erythematosus: Diagnostic and Therapeutic Challenges. [PDF]

Int Med Case Rep J
Resmi T, Suwarsa O, Sufiawati I.
europepmc   +1 more source

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

Pediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne, Thomas Hubiche, Jean‐Marie De Guillebon, Maella Severino‐Freire, Emmanuelle Bourrat, Sébastien Barbarot, Alice Phan, Christine Chiaverini   +7 more
wiley   +1 more source

Pyoderma Gangrenosum with Biological Agents Therapy: A Systematic Review. [PDF]

Clin Cosmet Investig Dermatol
Tan B, Chen M, Hu X, He J, Zhang L, Du S, Mou Y, Xiong X, Duan X.   +8 more
europepmc   +1 more source

Prescribing Patterns in Pediatric Hidradenitis Suppurativa

Pediatric Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin condition increasingly diagnosed in pediatric populations; however, data on treatment practices in this group remains limited. In this retrospective study of 163 patients diagnosed with HS ≤ 18 years of age, we found that treatment patterns varied significantly by disease severity.
Hannah Neimy, Courtney L. Walker, Lara Wine Lee, Colleen H. Cotton   +3 more
wiley   +1 more source

Successful Treatment of Comorbid SAPHO Syndrome and Hidradenitis Suppurativa with Upadacitinib. [PDF]

Acta Derm Venereol
Narayanan D, Tran T, Duque-Clavijo V, Doan HQ, Tyring SK.   +4 more
europepmc   +1 more source

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

Photochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman, Anju Meda, Kaitlyn A. Moore, Payal Srivastava, Anika Dasgupta, Andaleeb Sajid, Suresh V. Ambudkar, Huang‐Chiao Huang   +7 more
wiley   +1 more source