Results 51 to 60 of about 1,823 (213)
Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people: systematic review and economic evaluation [PDF]
, 2017 Background: Psoriasis is a chronic inflammatory disease that predominantly affects the skin. Adalimumab (HUMIRA®, AbbVie, Maidenhead, UK), etanercept (Enbrel®, Pfizer, New York, NY, USA) and ustekinumab (STELARA®, Janssen Biotech, Inc., Titusville, NJ ...
AbbVie +239 more
core +3 more sources
SMB Operation for Three-Fraction Separations: Purification of Plasmid DNA [PDF]
, 2018 The Simulated Moving Bed technology is extended to incorporate a cleaning in place step, and it is then applied by exploiting size exclusion chromatography to purify plasmid DNA.
Makart, Stefan +4 more
core
Inteins, valuable genetic elements in molecular biology and biotechnology [PDF]
, 2010 Inteins are internal protein elements that self-excise from their host protein and catalyze ligation of the flanking sequences (exteins) with a peptide bond. They are found in organisms in all three domains of life, and in viral proteins. Intein excision
Skander Elleuche, Stefanie Pöggeler
core +2 more sources
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim The role of systemic therapy in paediatric Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) remains undefined. Management is primarily guided by observational data and variable practice patterns. This systematic review aims to integrate recent evidence and evaluate clinical outcomes associated with systemic therapies in ...
Samantha Ting +3 more
wiley +1 more source
Engineering and Applications of fungal laccases for organic synthesis [PDF]
, 2008 Laccases are multi-copper containing oxidases (EC 1.10.3.2), widely distributed in fungi, higher plants and bacteria. Laccase catalyses the oxidation of phenols, polyphenols and anilines by one-electron abstraction, with the concomitant reduction of ...
Alcalde Miguel +5 more
core +3 more sources
Journal of Periodontal Research, EarlyView.Surgical treatment of refractory peri‐implant mucositis with a free gingival graft (FGG) was effective in disease resolution, achieving reductions in probing pocket depth (PPD) and inflammation. Significant gains in mucosal thickness (MT) and keratinized mucosa width (KMW), as well as partial recession coverage and re‐establishment of attached mucosa ...
Shayan Barootchi +7 more
wiley +1 more source
Network analysis of circular permutations in multidomain proteins reveals functional linkages for uncharacterized proteins. [PDF]
, 2014 Various studies have implicated different multidomain proteins in cancer. However, there has been little or no detailed study on the role of circular multidomain proteins in the general problem of cancer or on specific cancer types.
Adjeroh, Donald +3 more
core +3 more sources
Journal of Small Animal Practice, EarlyView.Objectives To report the clinicopathological findings, treatment and outcomes of Pugs diagnosed with protein‐losing enteropathy using VetCompass primary care clinical data in the UK and to determine if referral or any specific treatments for protein‐losing enteropathy were associated with outcome. Materials and Methods Retrospective VetCompass study of
A. Kathrani +3 more
wiley +1 more source
Anti-Trypanosoma cruzi effects of cyclosporin A derivatives: possible role of a P-glycoprotein and parasite cyclophilins [PDF]
, 2017 Cyclophilins are target molecules for cyclosporin A (CsA), an immunosuppressive antimicrobial drug. We have previously reported the in vitro anti-Trypanosoma cruzi activity of H-7-94 and F-7-62 non-immunosuppressive CsA analogues.
BÚA, J. +8 more
core
Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos [PDF]
, 2013 BACKGROUND: In mammals, ABCB1 constitutes a cellular “first line of defense” against a wide array of chemicals and drugs conferring cellular multidrug or multixenobiotic resistance (MDR/MXR).
Anne-Marie Schmidt +7 more
core +1 more source