Results 21 to 30 of about 236 (123)

Development of TR-19 Cyclotron Parameter Settings for Fully Automated Production of Radiometals with Applications in Nuclear Medicine

Instruments
At the Radiopharmaceutical Research Center (CCR) of the Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering (IFIN-HH), we operate a TR-19 cyclotron for radio isotope production.
Liviu Ștefan Crăciun, Tiberiu Relu Eșanu, Radu Leonte, Hermann Anton Schubert, Raul Victor Erhan, Dana Niculae   +5 more
doaj   +1 more source

Niobium as Preferential Material for Cyclotron Target Windows

Instruments
The present work promotes and validates the benefits of using niobium instead of Havar® as the material for the target windows in most routine irradiations in cyclotrons. Calculation of the material activation and measurements of the contamination of the
Sergio J. C. do Carmo, Francisco Alves
doaj   +1 more source

64Cu tumor labeling with hexadentate picolinic acid‐based bispidine immunoconjugates

Chemistry – A European Journal, Volume 30, Issue 32, June 6, 2024.
Bifunctional chelators based on bispidine picolinates allow rapid and efficient labeling with the positron emitter Cu‐64 under mild conditions. The resulting 64CuII‐labeled bispidine complexes exhibit high in vitro and in vivo stability. Isothiocyanate functionalization of bispidine picolinates in C9 position enables efficient coupling to targeting ...
Manja Kubeil, Christin Neuber, Miriam Starke, Claudia Arndt, Liliana Rodrigues Loureiro, Lydia Hoffmann, Anja Feldmann, Michael Bachmann, Jens Pietzsch, Peter Comba, Holger Stephan   +10 more
wiley   +1 more source

Improving cancer treatment with cyclotron produced radionuclides

, 1992
Our goal is to improve the scientific basis for tumor diagnosis, treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology.
Finn, R. D., Larson, S. M.
core   +1 more source

Production and Processing of the Radionuclide ⁷⁶Br

Instruments
Four-dimensional visualization, i.e., three-dimensional space plus time, of fluid flow and its interactions in geological materials using positron emission tomography (PET) requires suitable radiotracers that exhibit the desired physicochemical ...
Karsten Franke, Jann Schöngart, Alexander Mansel   +2 more
doaj   +1 more source

The role of chemistry in accelerator-based production and separation of radionuclides as basis for radiolabelled compounds for medical applications

, 2022
Radiochemical separations used in large scale routine production of diagnostic and therapeutic radionuclides at a particle accelerator for patient care are briefly outlined.
Spellerberg, Stefan, Neumaier, Bernd, Spahn, Ingo, Scholten, Bernhard, Qaim, Syed M.   +4 more
core   +1 more source

Cyclotron targetry for production of short-lived positron emitters [PDF]

, 1989
The basic concepts of cyclotron target design are presented along with the relevant practical experience gained by workers in this field over the years. Results are presented from several recent studies on the temperature and density distribution inside ...
Schlyer, David J.
core  

Improving cancer treatment with cyclotron produced radionuclides. Progress report

, 1992
Our goal is to improve the scientific basis for tumor diagnosis, treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology.
Finn, R. D., Larson, S. M.
core   +1 more source

Cyclotron production of short-lived radionuclides and labelled compounds for use in biomedical research and clinical diagnosis [PDF]

, 1994
The works submitted in this thesis cover the development of methods for the production in a cyclotron of a variety of radionuclides and their incorporation in radio-labelled compounds for use in biomedical research. In addition, papers are included which
Clark, John Charles
core  

Routine production of copper-64 using 11.7MeV protons

, 2016
Reliable production of copper-64 (64Cu) was achieved by irradiating enriched nickel-64 (64Ni, >94.8%) in an IBA 18/9 cyclotron. Nickel-64 (19.1 ± 3.0 mg) was electroplated onto an Au disc (125μm × 15mm).
Asad, Ali, Smith, Suzanne, Price, R.I., Chan, S., Jeffery, Charmaine   +4 more
core   +1 more source