Results 141 to 150 of about 6,219 (293)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Enabling Light-Weight Reasoning via Cypher Triggers

Deductive rules over graph data are a commonly accepted way to address complex reasoning tasks; among them, we mention the company control problem, which consists of determining who exercises control – directly or indirectly, through aggregation and ...
A. Colombo, L. Bellomarini, D. Martinenghi, D. Magnanimi, A. Bernasconi, S. Ceri   +5 more
core   +1 more source

NatureKG: an ontology and knowledge graph for nature finance with a Text2Cypher application. [PDF]

Front Artif Intell
Kushwaha N, Singh A, Sheikh HA.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Cypher\u27s Camps on West Branch

, 2013
Image scanned from black and white negative labeled Cypher\u27s Camps on West Branch. A wide lake, bisected by barriers, stretches between forested shores. There are hills in the far distance, and a wooden raft floating on the lake, as well as what may
Call, Bert
core  

Optimization of Cypher stent edge thickness from three-dimensional elasticity

U ovom radu detaljnije smo objasnili ulogu stenta u medicini. Pri tome je posebna pažnja posvećena Cypher stentu. Zatim smo s matematičke strane opisali zadaću koja opisuje deformaciju i pomak stenta pri djelovanju sila, pri čemu stent nije nigdje ...
Lovrić, Mirna
core   +1 more source

RAG-based architectures for drug side effect retrieval using compact LLMs. [PDF]

Sci Rep
Nygren S, Erdogan O, Avci P, Daniels A, Rassool R, Beheshti A, Galeano D.   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Swiss Infant Feeding Study (SWIFS) 2024

Vorstellung der Resultate der Swiss Infant Feeding Study (SWIFS) 2024 an der Lecture Series des Kompetenznetzwerkes Child and Youth Public Health Research ...
Juvalta, Sibylle, Grylka, Susanne, Dratva, Julia, Kalb, Veronica, Bruno, Silvia, Gross, Karin, Kerry-Krause, Matthew J., Jafflin, Kristen   +7 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source