Results 61 to 70 of about 7,267 (238)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Entre e nostalgia e a melancolia: paisagem, memória e futuro no rap nacional

open access: yesRumores, 2022
O presente trabalho investiga como os elementos discursivos e os estético-políticos da cypher Favela Vive, e de certa tradição do rap nacional, representam, na presença do território, a nostalgia e a melancolia.
Camila Campos Costa, Cláudio Coração
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Circles cypher photos

open access: yes, 2012
Circle's cypher photographs at the Phoenix Seal taken by Kevin Kosanovich on 09/10/2012. Raghav Veluri ran Circles, a William & Mary hip hop cultural event featuring a variety of hip-hop cultural styles performing together in a cypher.
Kosanovich, Kevin, 1981-
core  

Rechtliche Studie zum Cypher Social Contracts Konzept "Fides"

open access: yes, 2023
Rechtliche Studie zum Cypher Social Contracts Konzept und der Anwendung „Fides“
Dirk Müllmann   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

T-MEC en el espejo del TLCAN: Engañosas ilusiones, brutales realidades [PDF]

open access: yesOla Financiera, 2019
Se analiza fundamental el desempeño del Tratado de Libre Comercio de América del Norte, así como sus diferencias y convergencias con el Tratado México, Estados Unidos y Canadá de manera destacada en la industria automotriz y el efecto que se ha expresado
James M. Cypher, Mateo Crossa
doaj  

Structural and Hemodynamic Analyses of Different Stent Structures in Curved and Stenotic Coronary Artery

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Coronary artery stenting is commonly used for the treatment of coronary stenosis, and different stent structures indeed have various impacts on the stress distribution within the plaque and artery as well as the local hemodynamic environment.
Lingling Wei   +4 more
doaj   +1 more source

04.06.006: 3 domed buttons on card, George V Royal Cypher insignia

open access: yes, 1910
3 domed buttons on card, George V Royal Cypher insignia, brass, diameter 1.6cm [1910 ...

core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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