Results 51 to 60 of about 454 (98)

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Dodder seedlings benefit from apoplastic nutrition by inducing SWEET15‐mediated unloading of sucrose from the host's phloem

open access: yesNew Phytologist, Volume 252, Issue 2, Page 829-842, October 2026.
Cuscuta reflexa infection sites. Summary Cuscuta species are holoparasitic plants that penetrate host stems with haustoria, connect to the vasculature and exhaust water, nutrients and carbohydrates. Parasite seedlings possess only limited maternal reserves and the development of a vascular connection takes several days.
Maleen Hartenstein   +10 more
wiley   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu   +9 more
wiley   +1 more source

Variability of D2/D3 segment sequences of several populations and pathotypes of potato cyst nematodes (Globodera rostochiensis, Globodera pallida)

open access: yesPlant Protection Science, 2010
Potato cyst nematodes (Globodera rostochiensis, Globodera pallida) remain a key pest in the main potato growing regions of the Czech Republic. Due to difficult direct management and presence of diverse pathotypes attacking different potato cultivars the ...
Ondřej Douda   +4 more
doaj   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

open access: yesBiotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen   +2 more
wiley   +1 more source

A multi-omics approach reveals that the plant-parasitic nematode Globodera pallida can produce the phytohormone auxin IAA

open access: yesParasitology
The phytohormone auxin plays a crucial role in the development of so-called syncytia induced by cyst nematodes upon feeding on plant roots. However, it is unknown whether nematode-derived auxin contributes to plant parasitism by cyst nematodes. To do so,
Matthijs Oosterbeek   +6 more
doaj   +1 more source

Global‐Scale Patterns of Host Transitions Suggest Contrasting Levels of Specialization Within Rhizoctonia solani

open access: yesEcology and Evolution, Volume 16, Issue 9, September 2026.
We combined a global rDNA‐ITS dataset with TEF‐1α sequences and newly sequenced isolates to examine phylogenetic signal, host associations, and population structure in the soil‐borne pathogen Rhizoctonia solani. Most anastomosis groups formed well‐supported clades, and host‐associated patterns corresponded more strongly with genetic structure than ...
Xin Zhi Khoo   +2 more
wiley   +1 more source

Selective Packaging of miR‐22 and miR‐29 Orthologues into Extracellular Vesicles of the Porcine Whipworm Trichuris Suis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Helminths modulate host immunity, and in this respect, the porcine whipworm Trichuris suis has been explored clinically as an immunotherapy for inflammatory diseases. T. suis secretes a complex mixture of excretory/secretory products (ESP), including extracellular vesicles (EVs), nanosized membranous particles with bioactive cargoes of lipids,
Bradley Whitehead   +19 more
wiley   +1 more source

Naturally Induced Secretions of the Potato Cyst Nematode Co-stimulate the Proliferation of Both Tobacco Leaf Protoplasts and Human Peripheral Blood Mononuclear Cells

open access: yesMolecular Plant-Microbe Interactions, 1999
Naturally induced secretions from infective juveniles of the potato cyst nematode Globodera rostochiensis co-stimulate the proliferation of tobacco leaf protoplasts in the presence of the synthetic phytohormones α-naphtha-leneacetic acid (NAA) and 6 ...
Aska Goverse   +7 more
doaj   +1 more source

A Mechanism‐Based Framework for Anti‐Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell‐Based Interventions

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li   +4 more
wiley   +1 more source

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