Results 131 to 140 of about 975,983 (211)

Dioxygen reactivity and heme redox potential of truncated human cystathionine beta-synthase.

, 2008
Cystathionine beta-synthase (CBS) catalyzes the condensation of serine and homocysteine to cystathionine, which represents the committing step in the transsulfuration pathway.
Banerjee, Ruma, Madzelan, Peter, Alvarez, Beatriz, Radi, Rafael, Zinola, Carlos F, Graña, Martín, Carballal, Sebastián   +6 more
core   +1 more source

Recurrent venous thrombosis in an adolescent male with CBS mutation and persistent antiphospholipid antibody positivity: a case report

Thrombosis Journal
Homocysteine (Hcy) contributes to endothelial dysfunction and impaired thrombolysis, and genetic polymorphisms that elevate plasma Hcy concentrations have been linked to an increased risk of thrombosis. Notably, mutations in the cystathionine β-synthase (
Yuebing Wang, Ru Li, Chun Li
doaj   +1 more source

Amplification of phenylalanine hydroxylase and cystathionine beta-synthase transcripts in human peripheral lymphocytes by RT-PCR

, 1998
A simple, rapid, reliable and convenient method was developed to analyze the gene defects in Phenylketonuria (PKU) and Homocystinuria (HCU). In this method, illegitimately transcribed phenylalanine hydroxylase (PAH) and cystathionine beta-synthase (CBS ...
Devi, AR, Kondaiah, P, Devi, KS
core  

Enhancing Postharvest Quality of Fresh-Cut Changgen Mushrooms by Exogenous L-Cysteine Treatment: Aspects of Accumulating Amino Acids, Triggering Energy Metabolism and Enhancing Endogenous H₂S Regulation

Foods
As a rare and functional edible mushroom, the market potential of ready-to-eat fresh-cut Changgen mushrooms (Oudemansiella raphanipes) is booming in developing countries.
Xingchi Ma, Tianhao Li, Weijian Mao, Yu Zhang, Haoran Liu, Wenwen Jiang, Yanan Sun, Hao Yu, Fansheng Cheng, Dan Zhu   +9 more
doaj   +1 more source

MOESM1 of Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

, 2018
Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug ...
Bartosz Szczesny (16538), Amy Mrazek (5816378), Nadiya Druzhyna (5816381), Celia Chao (525874), John Zatarain (5816372), Mark Hellmich (5816405), Kazunori Yanagi (2364097), Gabor Olah (459086), Paul Johnson (350591), Jia Zhou (53252), Ciro Coletta (5816375), Akbar Ahmad (395893), Judy Hellmich (5816384), Gabor Törö (5816390), David Eckelbarger (5816399), Rachel Lewis (246649), Katalin Módis (422088), Minal Cheema (5816396), Fredrick Bohanon (5816393), Haiying Chen (9771), Csaba Szabo (422091), Petra Szoleczky (422087), Antonia Asimakopoulou (5816387), Ye Ding (40594), Andreas Papapetropoulos (77896), Ashley Untereiner (5816402)   +25 more
core   +1 more source

A liquid chromatography mass spectrometry method for the measurement of cystathionine beta-synthase activity in cell extracts

, 2012
Item does not contain fulltextBackground: In order to correctly assess the efficacy of therapy or diet in intervention studies on the activity of cystathionine beta-synthase (CBS) a sensitive analytical method is necessary. Methods: An electrospray LC-MS/
Kluijtmans, L.A.J., Janssen, M.C.H., Mendes, M.I., Blom, H.J., Smith, D.E., Smulders, Y.M.   +5 more
core   +1 more source

Pyridoxine non-responsive R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype.

Biochimica et Biophysica Acta - General Subjects, 2022
D. Al-Sadeq, Angelos Thanassoulas, Z. Islam, P. Kolatkar, Nader Al-Dewik, B. Safieh-Garabedian, Gheyath K. Nasrallah, M. Nomikos   +7 more
semanticscholar   +1 more source

Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes.

, 2001
International audienceInteraction of rat and human cystathionine-beta-synthase (CBS) with various potential ligands has been studied by visible and EPR spectroscopy in order to explore the coordination chemistry of this atypical hemeprotein.
Delaforge, M., Boucher, Jl, Janosik, M., Vadon-Legoff, S., Mansuy, D., Kraus, Jp   +5 more
core   +1 more source

Hydrogen sulfide and its role in female reproduction

Frontiers in Veterinary Science
Hydrogen sulfide (H2S) is a gaseous signaling molecule produced in the body by three enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Aneta Pilsova, Zuzana Pilsova, Barbora Klusackova, Natalie Zelenkova, Eva Chmelikova, Pavla Postlerova, Marketa Sedmikova   +6 more
doaj   +1 more source

A revisit to the natural history of homocystinuria due to cystathionine beta-synthase deficiency

, 2010
We review the evidence that in Denmark and probably certain other European countries the number of individuals identified with homocystinuria due to homozygosity for the widespread c.833T>C (p.I278T) mutation in the gene that encodes cystathionine ...
Gaustadnes, Mette, Skovby, Flemming, Mudd, S Harvey   +2 more
core   +1 more source