Results 171 to 180 of about 7,388 (204)

Cystathionine gamma lyase expression/activity delays endothelial senescence

Free Radical Biology and Medicine, 2022
Sofia Bibli, Jiong Hu, Matthias Leisegang, Ilka Wittig, Ralf Brandes, Andreas Papapetropoulos, Fragiska Sigala, Ingrid Fleming   +7 more
openaire   +1 more source

Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages

Cellular and Molecular Life Sciences, 2010
Hydrogen sulfide (H(2)S) plays an important role in inflammation. We showed that macrophages expressed the H(2)S-forming enzyme cystathionine gamma-lyase (CSE) and produced H(2)S. Lipopolysaccharide (LPS) stimulated the CSE expression and H(2)S production rate. l-cysteine reduced LPS-induced nitric oxide (NO) production.
Xiao-Yan, Zhu, Shu-Juan, Liu, Yu-Jian, Liu, Shan, Wang, Xin, Ni   +4 more
openaire   +2 more sources

P35 Exacerbation of the septic response in cystathionine-gamma-lyase deficient mice

Nitric Oxide, 2014
Previous studies reported both beneficial and detrimental roles of hydrogen sulfide (H2S) in various models of critical illness. The goal of our study was to compare the outcome of septic shock in wild-type mice and in mice deficient in cystathionine-gamma-lyase (CSE).
Ciro Coletta, Csaba Szabo
openaire   +1 more source

Changes in cystathionine gamma-lyase levels in rat liver during lactation.

Biochemistry and molecular biology international, 1994
Rat liver cystathionine gamma-lyase activity increased rapidly with the onset of lactation, reaching a maximum value at week 2 and slowly decreasing thereafter. In non-lactating rats, from which the litters had been removed on the day of birth, the activity of this enzyme increased only minimally.
S, Awata, K, Nakayama, A, Sato, M, Kawamura, I, Suzuki, H, Kodama   +5 more
openaire   +1 more source

SARS-CoV-2 variant biology: immune escape, transmission and fitness

Nature Reviews Microbiology, 2023
Alessandro Maria Carabelli, William T Harvey, Joseph Hughes   +2 more
exaly  

A kilonova following a long-duration gamma-ray burst at 350 Mpc

Nature, 2022
Jillian Rastinejad, B P Gompertz, Daniele Malesani   +2 more
exaly  

Cystathionine gamma-lyase

1990
Dietmar Schomburg, Margit Salzmann
openaire   +1 more source

Development of a versatile and efficient C–N lyase platform for asymmetric hydroamination via computational enzyme redesign

Nature Catalysis, 2021
Ying-Lu Cui, Tong Zhu, Bian Wu
exaly  

Mechanism of S-(carboxymethylthio)cysteine cleavage by rat liver cystathionine-gamma-lyase.

Physiological chemistry and physics, 1979
Rat liver cystathionine-gamma-lyase [L-cystathionine cysteinelyase (deaminating), EC 4.4.1.1] catalyzes the formation of pyruvic acid, ammonia, and carboxymethylhydrodisulfide from S-(carboxymethylthio)cysteine (CMTC). As judged by pyruvic acid production, the optimal pH is 8.3 in tris-HCl buffer and the Km is 2.9 mM.
K, Yao, M, Kinuta, Y, Watanabe
openaire   +1 more source

Endogenous cystathionine-gamma-lyase/hydrogen sulfide pathway regulates apoptosis of HepG2 cells.

Yao xue xue bao = Acta pharmaceutica Sinica, 2016
This study is to investigate the role of endogenous CSE/H2S in regulating apoptosis of HepG2 cells. MTT and Trypan blue assay were performed to determine the effect of CSE inhibitor PAG and CSE siRNA on proliferation of HepG2. Production of H2S from HepG2 cells was assessed spectrophotometrically using N, N-dimethyl-p-phenylenediamine-dihydrochloride ...
Tian-Xiao, Wang, Xiao-Yan, Shi, Ying-Hua, Liu   +2 more
openaire   +1 more source