Results 171 to 180 of about 55,204 (241)

Determination of Glomerular Filtration Rate After Contrast-Enhanced CT Among Critically Ill Patients: Support for a New Procedure. [PDF]

Crit Care Explor
Kågedal B, Helldén A, Nezirević Dernroth D, Lindgaard Andersen A, Ekman A, Haglund M, Kataria B, Oskarsson F, Tobieson L, Östholm Å, Hanberger H.   +10 more
europepmc   +1 more source

Implementing use of cystatin C‐guided estimated glomerular filtration rate for medication dosing at an Academic Medical Center

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 8, Issue 5, Page 376-384, May 2025.
Abstract Accurate kidney function assessment is essential for medication dosing, although traditional methods such as urine output and serum creatinine are limited, especially in patients with acute kidney injury. Cystatin C was made available as an alternative marker at our institution, prompting the formation of a multidisciplinary task force to ...
Victoria Williams, Rupal Parbhoo, Bruce Doepker, Claire Murphy, Lynn Wardlow, Kevin Kissling, Megan Bond, Kelly Bartsch, Sree Satyapriya, Markisha Wilder, Jessica Greco, Anthony Gerlach   +11 more
wiley   +1 more source

Is Retinol Binding Protein 4 a Good Biomarker of Renal Function in Children with Neurogenic Bladder After Myelomeningocele? [PDF]

J Clin Med
Szymańska A, Bagińska-Chyży J, Korzeniecka-Kozerska A.   +2 more
europepmc   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

Experimental Physiology, EarlyView.
Anders Møller Greve, Anna Agnes Lytzen, Hrefna Sæunn Einarsdóttir, Michael Perch, Ronan M. G. Berg   +4 more
wiley   +1 more source

Results of the ACTION‐Galactosemia Kids Study to Evaluate the Effects of Govorestat in Pediatric Patients with Classic Galactosemia

The Journal of Clinical Pharmacology, Volume 65, Issue 5, Page 575-587, May 2025.
Abstract To evaluate the pharmacodynamic effects and clinical outcomes of orally administered once‐daily govorestat (AT‐007), a central nervous system penetrant aldose reductase inhibitor, the double‐blind placebo‐controlled ACTION‐Galactosemia Kids study (NCT04902781) randomly assigned 47 participants (2‐17 years old) with Classic Galactosemia to 18 ...
Evan Bailey, Han Phan, Ayesha Ahmad, Janet Thomas, Elizabeth G. Ames, Amanda B. Pritchard, Shane C. Quinonez, Stella Wang, Caleb Dayley, Andrew Salt, Christina Pick, Abe Durrant, Samuel Johnson, Jessie Nicodemus‐Johnson, Samuel P. Dickson, Riccardo Perfetti, Suzanne B. Hendrix, Shoshana Shendelman   +17 more
wiley   +1 more source

Value of blood biomarkers in the diagnosis of Parkinson's disease: a case-control study from Xinjiang. [PDF]

BMC Neurol
Wei R, Zhang Y, Li P, Aisha A, Nuerlanbieke H, Niyazi A, Yuan Y, Wu Q, Cao M.   +8 more
europepmc   +1 more source

Successful Pregnancy Management of a Woman With Severe Methylmalonic Acidemia

JIMD Reports, Volume 66, Issue 3, May 2025.
ABSTRACT Isolated methylmalonic acidemia (MMA) is a rare, genetically heterogeneous group of metabolic disorders resulting from a deficiency of the enzyme methylmalonyl‐CoA mutase (MMUT), defects in the metabolism of its cofactor, adenosylcobalamin, or deficiency of the enzyme methylmalonyl‐CoA epimerase. With improved awareness, earlier diagnosis, and
M. Woidy, K. Tsiakas, M. Mahmud, G. Eich, S. Loos, J. Lisfeld, S. Schultz, A. C. Tallarek, K. Hecher, T. B. Huber, A. C. Muntau, G. Gramer   +11 more
wiley   +1 more source

Correlation between chronic kidney disease and all-cause mortality in diabetic foot ulcers: evidence from the 1999-2004 national health and nutrition examination survey (NHANES). [PDF]

Front Endocrinol (Lausanne)
Liang J, An H, Hu X, Gao Y, Zhou J, Gong X, Zong J, Liu Y.   +7 more
europepmc   +1 more source

N‐terminomics and proteomics analysis of Calpain‐2 reveal key proteolytic processing of metabolic and cell adhesion proteins

Protein Science, Volume 34, Issue 5, May 2025.
Abstract Aberrant levels of the cysteine protease Calpain‐2 have been linked to neurodegeneration, inflammation, and cancer, yet our understanding of this protease and its substrates remains limited. Systematic studies to identify Calpain‐2 substrates have been largely confined to peptide libraries or in vitro studies, which fail to represent ...
Anjali Kapilan, Mitchell Bulluss, Alexander R. Ziegler, Mohamed Dabaja, Afshin Derakhshani, Anthonia Anowai, Victoria Armstrong, Rhiannon Campden, Daniel Young, Young Joo Sun, Nichollas E. Scott, Laura E. Edgington‐Mitchell, Vinit B. Mahajan, Antoine Dufour   +13 more
wiley   +1 more source

Association between elevated cystatin C levels and obstructive sleep apnea hypopnea syndrome: a systematic review and updated meta-analysis. [PDF]

BMC Pulm Med
Fu N, Tan X, He J.
europepmc   +1 more source