Differential Organ Ageing Is Associated With Age‐Related Macular Degeneration
Using the UK Biobank, this study trained neural networks to estimate the biological age of individuals according to markers of organ function. Computing the difference between the estimated organ age and chronological age yielded an estimate for accelerated or slowed ageing.
Anastasios Papadam+2 more
wiley +1 more source
Interaction of Cystatin C Variants with Papain and Human Cathepsins B, H and L
Nina Cimerman+5 more
openalex +1 more source
Analytical Performance of a Particle-enhanced Nephelometric Immunoassay for Serum Cystatin C Using Rate Analysis [PDF]
Helen J Stowe+3 more
openalex +1 more source
Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel+17 more
wiley +1 more source
Folding-related Dimerization of Human Cystatin C
Irena Ekiel, Magnus Abrahamson
openalex +1 more source
Effects of Glucocorticoid Immunosuppression on Serum Cystatin C Concentrations in Renal Transplant Patients [PDF]
Lorenz Risch+3 more
openalex +1 more source
Integration of multi‐omics analyses reveals PDAP1 as one of the key regulators of longevity and aging. Mendelian randomization, colocalization, prospective studies, and in vitro experiments highlight PDAP1's effects on mortality, lifespan, and cellular senescence.
Tianzhichao Hou+18 more
wiley +1 more source
Expression of Cysteine Proteinases Cathepsins B and K and of Cysteine Proteinase Inhibitor Cystatin C in Giant Cell Tumor of Tendon Sheath [PDF]
Torsten Hansen+6 more
openalex +1 more source
The Lipidomic Profile Discriminates Between MASLD and MetALD
HDL‐centric lipidomic biomarkers, particularly within large and medium HDL subfractions, distinguish metabolic dysfunction and alcohol‐related liver disease from metabolic dysfunction‐associated steatotic liver disease, suggesting potential biomarkers for clinical differentiation.
Kai Markus Schneider+15 more
wiley +1 more source
Reference Intervals for Plasma Cystatin C in Healthy Volunteers and Renal Patients, as Measured by the Dade Behring BN II System, and Correlation with Creatinine [PDF]
Erik J. Uhlmann+6 more
openalex +1 more source