Results 221 to 230 of about 38,749 (246)

Cystatin C in pre-eclampsia

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
To evaluate diagnostic value of cystatin C serum levels as alternative marker of renal function in pre-eclamsia (PE) and compare it with the traditional markers of renal function, creatinine and uric acid. In order to investigate the possible influence of inflammation on biochemical markers of renal function, serum levels of high sensitive CRP were ...
Aleksandra, Novakov Mikic, Velibor, Cabarkapa, Aleksandra, Nikolic, Daniela, Maric, Snezana, Brkic, Gorana, Mitic, Marina, Ristic, Zoran, Stosic   +7 more
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Assessment of cystatin C and cystatin C-based GFR formulas in reflux nephropathy

Journal of Pediatric Urology, 2014
Early identification of reflux nephropathy (RN) could reduce the frequency of chronic kidney disease (CKD) caused by vesicoureteral reflux (VUR). We aimed to assess whether cystatin C has value for determining RN in children with VUR.Ninety-three children with VUR were classified into two groups according to the presence of renal parenchymal scarring ...
Yavuz S., Anarat A., Bayazit A.K.
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Cystatin C: our experience

Pediatric Nephrology, 2005
Sirs, We have read with interest a number of contributions in recent issues of the journal [1, 2, 3] pointing out that cystatin C remains a current issue. We therefore present our own results concerning this problem. Cystatin C (cysC) is low molecular protein which is recognized as a good indicator of glomerular filtration rate (GFR) by most authors [4]
Snežana Pavićević, Amira Peco-Antić
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Different Forms of Human Cystatin C

Biological Chemistry Hoppe-Seyler, 1990
Two isoelectric forms of human cystatin C with pI 9.2 and 7.8 have been isolated from urine of patients with different nephrological disorders. Treatment of both forms with alkaline phosphatase revealed that the difference between them is not due to the phosphorylation of some amino-acid residue.
T, Popović, J, Brzin, A, Ritonja, V, Turk   +3 more
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Improved immunoturbidimetric assay for cystatin C

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2001
An immunoturbidimetric assay for cystatin C was optimized with respect to assay imprecision. After investigating the optimum pH, polyethylene glycol concentration and specimen volume, two modifications were introduced: an increase in specimen volume to 25 µL; and an extension of the pre-incubation period to 240s.
A V, Lewis, T J, James, J B, McGuire, R P, Taylor   +3 more
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Cystatin C reference values and aging

Clinical Biochemistry, 2006
The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected.CysC showed a significant correlation with age
Ognibene, Agostino, MANNUCCI, EDOARDO, CALDINI, ANNA, TERRENI, ALESSANDRO, BROGI, MARCO, BARDINI, GIANLUCA, Sposato, Iolanda, Mosconi, Valentina, SALVADORI, BENEDETTA, ROTELLA, CARLO MARIA, Messeri, Gianni   +10 more
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Cystatin C modulates cerebral β-amyloidosis

Nature Genetics, 2007
The CST3 Thr25 allele of CST3, which encodes cystatin C, leads to reduced cystatin C secretion and conveys susceptibility to Alzheimer's disease. Here we show that overexpression of human cystatin C in brains of APP-transgenic mice reduces cerebral amyloid-beta deposition and that cystatin C binds amyloid-beta and inhibits its fibril formation.
Stephan A, Kaeser, Martin C, Herzig, Janaky, Coomaraswamy, Ellen, Kilger, Maj-Linda, Selenica, David T, Winkler, Matthias, Staufenbiel, Efrat, Levy, Anders, Grubb, Mathias, Jucker   +9 more
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Cystatin C in acute kidney injury

Current Opinion in Critical Care, 2010
This review will summarize and discuss the role of cystatin C in the diagnosis of acute kidney injury.Cystatin C is easily measured and has the characteristics of an ideal marker of kidney function. Data suggest that cystatin C is modified by age, sex, muscle mass, obesity, smoking status, thyroid function, inflammation, and malignancy.
Sean M, Bagshaw, Rinaldo, Bellomo
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Clinical value of cystatin C determination

Clinica Chimica Acta, 2000
It has been reported that cystatin C (cys-C) is elevated in patients with malignant disease. In order to investigate whether this phenomenon is linked to or independent of renal function, and at the same time examine the role of this marker in other pathological situations, cys-C concentrations were compared with 24-h creatinine clearance values in ...
M K, Page, J, Bükki, P, Luppa, D, Neumeier   +3 more
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No mutations in cystatin C gene in cerebral amyloid angiopathy with cystatin C deposition

Molecular and Chemical Neuropathology, 1998
To investigate the relationship between cerebral amyloid angiopathy (CAA) and cystatin C, we studied five CAA patients on whose cerebral blood vessels colocalization of cystatin C and beta-protein was recognized immunohistochemically. One patient was suspected as familial CAA and the other patients were sporadic cases.
A, Nagai, S, Kobayashi, K, Shimode, K, Imaoka, N, Umegae, S, Fujihara, M, Nakamura   +6 more
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