Results 111 to 120 of about 25,149 (297)
Low density lipoprotein oxidation by ferritin at lysosomal pH [PDF]
, 2018 Oxidation of low density lipoprotein (LDL) has been proposed to be involved in the pathogenesis of atherosclerosis. We have previously shown that LDL can be oxidised by iron in lysosomes.
Leake, David S., Ojo, Oluwatosin O.
core +1 more source
Frontiers in Immunology, 2020 Host-directed therapies (HDTs) are emerging as a potential valid support in the treatment of drug-resistant tuberculosis (TB). Following our recent report indicating that genetic and pharmacological inhibition of transglutaminase 2 (TG2) restricts ...
Ivana Palucci +21 more
doaj +1 more source
SYNTHESIS AND CHARACTERIZATION OF HYDROXYPROPYL CELLULOSE-CYSTEAMINE CONJUGATE AS A NOVEL CATIONIC THIOMER WITH LIPOPHILIC PROPERTIES [PDF]
, 2019 Objective: Thiomers have been known as polymer with mucoadhesive properties. The aim of this study was to synthesize the mucoadhesive potential of hydroxypropyl cellulose-cysteamine conjugate (HPC-cysteamine).Methods: The parent polymer HPC was ...
Laksmitawati, Dian Ratih +3 more
core +1 more source
Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures [PDF]
, 2004 The aim of this study was to evaluate the involvement of oxidative stress in glutamate-evoked transglutaminase (TGase) upregulation in astrocyte cultures (14 DIV).
Avola, R. +7 more
core +1 more source
A Pseudo‐catalytic Network Motif for Thiol‐based Chemical Reaction Networks
ChemSystemsChem, Volume 7, Issue 2, March 2025.The synthesis of chemical reaction networks (CRNs) is a challenging task. Herein, we designed a pseudo‐catalytic network motif for thiol‐based CRNs. This motif involves the reaction between organic thiocyanates and cystamine. Due to the nucleophilic chain mechanism, the rate of this reaction is proportional to the concentration of thiols in the system.
Ekaterina A. Zhigileva +2 more
wiley +1 more source
Human Molecular Genetics, 2019 Cysteamine bitartrate is a US Food and Drug Administration-approved therapy for nephropathic cystinosis also postulated to enhance glutathione biosynthesis.
Sujay Guha +14 more
semanticscholar +1 more source
International Journal of Cosmetic Science, EarlyView.We have discovered 2‐(2‐aminoethylthio) succinic acid with a long‐lasting hair shape control effect. We have demonstrated its hair straightening and curl retention effect, and clarified its mechanism. Abstract Objective Hair is a crucial aspect of an individual's physical appearance.
Sotaro Sato +11 more
wiley +1 more source
A Review on the Antimutagenic and Anticancer Effects of Cysteamine
Advances in Pharmacological and Pharmaceutical Sciences, 2023 Cancer is one of the leading causes of death worldwide. First-line treatments usually include surgery, radiotherapy, and/or systemic therapy. These methods can be associated with serious adverse events and can be toxic to healthy cells. Despite the new advances in cancer therapies, there is still a continuous need for safe and effective therapeutic ...
openaire +3 more sources
Pathogenesis of Melasma Explained
International Journal of Dermatology, EarlyView.Pathophysiology of melasma. ABSTRACT This review provides an in‐depth analysis of the pathophysiology of melasma and highlights recent studies that elucidate its underlying mechanisms. Given the prevalence of melasma, a thorough understanding of its pathogenesis is critical for the development of effective treatment strategies.
Lara Ali, Firas Al Niaimi
wiley +1 more source
Journal of Biomedical Nanotechnology, 2019 Copper-cysteamine (Cu-Cy) nanoparticles (NPs) are a new type of sensitizers that can be activated by UV light, X-rays, microwaves and ultrasound to produce reactive oxygen species for cancer treatment.
Liyi Huang +6 more
semanticscholar +1 more source