Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate [PDF]
Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis. Recently, an enteric coated formulation of cysteamine bitartrate (RP103) administered twice daily was demonstrated to be non-inferior ...
Besouw, Martine+4 more
core +1 more source
A Review on the Antimutagenic and Anticancer Effects of Cysteamine
Cancer is one of the leading causes of death worldwide. First-line treatments usually include surgery, radiotherapy, and/or systemic therapy. These methods can be associated with serious adverse events and can be toxic to healthy cells. Despite the new advances in cancer therapies, there is still a continuous need for safe and effective therapeutic ...
openaire +3 more sources
Multiparametric analysis is a crucial aspect for enhancing the final sensitivity of biosensors based on organic transistors. The traditional approaches to treat the experimental data are not always suitable to extract the correct response. In this work EGOT characteristics are processed to achieve enantiodiscrimination of free Tryptophan enantiomers ...
Matteo Genitoni+9 more
wiley +1 more source
alpha -Lactalbumin (LA) Stimulates Milk beta-1,4-Galactosyltransferase I (beta 4Gal-T1) to Transfer Glucose from UDP-glucose to N-Acetylglucosamine: CRYSTAL STRUCTURE OF beta 4Gal-T1·LA COMPLEX WITH UDP-Glc* [PDF]
beta-1,4-Galactosyltransferase 1 (Gal-T1) transfers galactose (Gal) from UDP-Gal to N-acetylglucosamine (GlcNAc), which constitutes its normal galactosyltransferase (Gal-T) activity.
Qasba, Pradman K.+2 more
core
A Pseudo‐catalytic Network Motif for Thiol‐based Chemical Reaction Networks
The synthesis of chemical reaction networks (CRNs) is a challenging task. Herein, we designed a pseudo‐catalytic network motif for thiol‐based CRNs. This motif involves the reaction between organic thiocyanates and cystamine. Due to the nucleophilic chain mechanism, the rate of this reaction is proportional to the concentration of thiols in the system.
Ekaterina A. Zhigileva+2 more
wiley +1 more source
Cysteamine bitartrate is a US Food and Drug Administration-approved therapy for nephropathic cystinosis also postulated to enhance glutathione biosynthesis.
Sujay Guha+14 more
semanticscholar +1 more source
Emerging Biosensor Technologies for Stroke Biomarker Detection: A Comprehensive Overview
ABSTRACT Stroke remains a leading cause of morbidity and mortality worldwide, necessitating the development of rapid and reliable diagnostic tools for early detection and management. This manuscript presents an overview of innovative biosensors designed for the detection of key stroke biomarkers, including N‐terminal pro B‐type natriuretic peptide (NT ...
Ghazal Koohkansaadi+3 more
wiley +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng+10 more
wiley +1 more source
The Interaction of Cysteamine and Cysteine with various Carbonyl Compounds. [PDF]
L. Eldjarn+6 more
openalex +1 more source
Copper-cysteamine (Cu-Cy) nanoparticles (NPs) are a new type of sensitizers that can be activated by UV light, X-rays, microwaves and ultrasound to produce reactive oxygen species for cancer treatment.
Liyi Huang+6 more
semanticscholar +1 more source