Results 241 to 250 of about 25,149 (297)

Solution-Based SERS Detection of Weak Surficial Affinity Molecules Using Cysteamine-Modified Au Bipyramids.

Analytical Chemistry, 2021
To achieve ultrasensitive detection of trace targets through solution-based surface-enhanced Raman spectroscopy (SERS), direct adsorption of the target molecules on a SERS-active surface is vital.
M. Amin, Ruiyuan Zhang, Lingwei Li, H. You, J. Fang   +4 more
semanticscholar   +1 more source

Topical Stabilized Cysteamine as a New Treatment for Hyperpigmentation Disorders: Melasma, Post-Inflammatory Hyperpigmentation, and Lentigines.

Journal of Drugs in Dermatology, 2021
Cysteamine is an aminothiol naturally present in cells of the human body as an antioxidant resulting from the degradation of Coenzyme A. Physiologically it is well distributed in mammalian tissues. Highly concentrated in human milk, cysteamine acts as an
S. Desai, Corey L Hartman, P. Grimes, Sana Shah   +3 more
semanticscholar   +1 more source

Efficacy of topical cysteamine hydrochloride in treating melasma: a systematic review

Journal of Cosmetic Dermatology, 2021
Melasma remains a recurrent, chronic, therapeutically challenging, and psychologically burdening condition. Several different modalities and approaches have been utilized, and some with notable success to experimentally manage the condition. Cysteamines,
Najmeh Ahramiyanpour, N. Saki, Z. Akbari, S. Shamsi-meymandi, Rezvan Amiri, Alireza Heiran   +5 more
semanticscholar   +1 more source

Radiation Protection of Tissue Culture Cells by Anoxia, Cysteamine and a Combination of Anoxia and Cysteamine [PDF]

Nature, 1962
Evidence is given in support of the hypothesis that the radioprotective action of a group of sulfhydryl compounds such as cysteine and cysteamine is not based on the removal of oxygen but is caused by another mode of action on the cellular level. In the experiments, cysteamine in concentrations of 4 and 16 mM- bar gave dose reduction factors of 1.8 and
O. Vos, L. Budke, A.J. Vergroesen
openaire   +2 more sources

Cysteamine and cystamine

1987
Publisher Summary This chapter discusses about cysteamine and cystamine. Cysteamine (2-aminoethanethiol) is formed in mammalian tissues by the enzymatic hydrolysis of pantetheine, and has the role in the biosynthesis of hypotaurine. Cysteamine has been used therapeutically to treat cystinosis and sickle cell anemia, and has been used as a protective ...
Michael W. Duffel, Daniel J. Logan, Daniel M. Ziegler   +2 more
openaire   +3 more sources

Treatment of cystinosis with cysteamine

The Journal of Pediatrics, 1979
C v s T I N 0 S I S is a recessively inherited metabolic disorder characterized by an accumulation of nonprotein cystine within the lysosomes. 1 ! n the juvenile nephropathic form, the disease presents with tubular renal dysfunction and progressive glomerular damage, leading to end-stage renal failure and eventual death.
M.S. DeWolfe, J.F.S. Crocker, E.P. Girardin   +2 more
openaire   +3 more sources

Cysteamine Toxicity in Patients with Cystinosis

The Journal of Pediatrics, 2011
To report new adverse effects of cysteamine.Detailed clinical information was obtained from the patients' physicians.New adverse events were reported in 8 of 550 patients with cystinosis treated with cysteamine in Europe during the last 5 years. Detailed clinical information was not available for 2 of these patients, 1 of whom died from cerebral ...
Besouw, M.T., Bowker, R., Dutertre, J.P., Emma, F., Gahl, W.A., Greco, M., Lilien, M.R., McKiernan, J., Nobili, F., Schneider, J.A., Skovby, F., van den Heuvel, L.P., van den Heuvel, L.P., van 't Hoff, W.G., Levtchenko, E.N.   +14 more
openaire   +5 more sources

Evaluation of the efficacy of cysteamine cream compared to hydroquinone in the treatment of melasma: A randomised, double‐blinded trial

Australasian Journal of Dermatology, 2020
Melasma is a commonly acquired disorder of hyperpigmentation that often poses a therapeutic challenge for dermatologists. Recently, cysteamine cream has shown promising results compared to placebo.
J. Nguyen, L. Remyn, I. Chung, A. Honigman, Shima Gourani-Tehrani, I. Wutami, Celestine C Wong, E. Paul, M. Rodrigues   +8 more
semanticscholar   +1 more source

A comparative study of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women

International Journal of Dermatology, 2020
To assess the efficacy and safety of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women. Topical 5% cysteamine is an antioxidant and tyrosinase inhibitor that has been shown to be effective in the treatment of ...
P. B. Lima, J. A. F. Dias, D. Cassiano, A. Espósito, E. Bagatin, L. Miot, H. Miot   +6 more
semanticscholar   +1 more source

Clinical evaluation of efficacy, safety and tolerability of cysteamine 5% cream in comparison with modified Kligman’s formula in subjects with epidermal melasma: A randomized, double‐blind clinical trial study

Skin research and technology, 2020
Kligman’s formula (KF) remains to date the dermatologists’ treatment of choice for melasma. This study was aimed at the evaluation of the effectiveness of Modified Kligman’s formula (MKF) in comparison with cysteamine 5% cream on the severity of ...
Maryam Karrabi, J. David, M. Sahebkar
semanticscholar   +1 more source