Results 51 to 60 of about 11,095 (222)

Cysteamine prevents vascular leakage through inhibiting transglutaminase in diabetic retina [PDF]

open access: yes, 2017
Cysteamine (an aminothiol), which is derived from coenzyme A degradation and metabolized into taurine, has beneficial effects against cystinosis and neurodegenerative diseases; however, its role in diabetic complications is unknown.
Seok-Ho Hong   +8 more
core   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Formulation study of cysteamine microparticulate systems [PDF]

open access: yes, 2020
Cysteamine is clinically used for the treatment of nephropathic cystinosis and is orally administered as cysteamine bitartrate. The daily dose of cysteamine (Cystagon®) for treatment of cystinosis in paediatric patients is 50 mg/kg per day, shared in ...
Adorni, Greta
core  

Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone [PDF]

open access: yes, 2001
Recently, we showed cysteamine-duodenal lesions without gastric acid, since they were induced also in gastrectomized rats, as in naive rats, and they were inhibited by the novel stomach pentadecapeptide BPC 157 as well as standard antiulcer drugs (i.e ...
Sven Seiwerth   +27 more
core   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

open access: yesAngewandte Chemie, Volume 138, Issue 30, 20 July 2026.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng   +4 more
wiley   +2 more sources

The effects of cysteamine on in vitro production of embryos from rare breed hanwoo (albino White and Black) ovum pick-up and slaughterhouse derived oocytes

open access: yesJournal of Animal Reproduction and Biotechnology, 2016
Historically, Korea old cattle had been consisted with various lines of coat color brindle, black and white-brown breeds or more. The two rare lines of black and white coat color are maintained for animal resources and preserved critically.
Sung Woo Kim   +5 more
doaj   +1 more source

Efficacy and safety of cysteamine-isobionicamide complex in postinflammatory hyperpigmentation: A 16-week, randomized, double-blinded, vehicle-controlled trial

open access: yesDermatologica Sinica, 2023
Background: Postinflammatory hyperpigmentation (PIH) is a prevalent acquired hyperpigmentation disorder with significant psychosocial implications. Cysteamine has demonstrated notable efficacy and safety in treating hyperpigmentation disorders.
Rosalie Tzu-Li Liu   +3 more
doaj   +1 more source

Cysteamine functionalised reduced graphene oxide modification of maleated poly(propylene) [PDF]

open access: yes, 2020
Graphene oxide (GO) was reduced (rGO) and then functionalised with an amino terminated thiol molecule (cysteamine) via a thiol-ene click chemistry reaction to produce reduced graphene oxide-cysteamine (rGO-cyst). The presence of the C–S bond in the X-ray
Abbas, Syeda   +4 more
core   +1 more source

Three Component Thio‐ and Carboboration of Alkynes: A Modular Route to Functionalised Bicyclic Boronates

open access: yesAngewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Three‐component thio‐ and carbo‐boration reactions to form functionalised benzoxaborinines and benzazaborinines are reported. The nucleophile scope includes thioethers, thiols, and (hetero)arenes. Mechanistic studies revealed a disparity between thioboration using thioethers and using thiols.
Laura Winfrey   +4 more
wiley   +2 more sources

Immunomodulatory effects of cysteamine and its potential use as a host-directed therapy for tuberculosis

open access: yesFrontiers in Immunology
ObjectiveCysteamine, a drug approved to treat cystinosis, has been proposed as a host-directed therapy for M. tuberculosis (Mtb) and SARS-CoV-2. The impact of cysteamine on the immune responses has not been fully investigated.
Saeid Najafi-Fard   +14 more
doaj   +1 more source

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